Test-retest reliability of the default mode network in a multi-centric fMRI study of healthy elderly

Effects of data-driven physiological noise correction techniques

Rocco Marchitelli, Ludovico Minati, Moira Marizzoni, Beatriz Bosch, David Bartrés-Faz, Bernhard W. Müller, Jens Wiltfang, Ute Fiedler, Luca Roccatagliata, Agnese Picco, Flavio Nobili, Oliver Blin, Stephanie Bombois, Renaud Lopes, Régis Bordet, Julien Sein, Jean Philippe Ranjeva, Mira Didic, Hélène Gros-Dagnac, Pierre Payoux & 25 others Giada Zoccatelli, Franco Alessandrini, Alberto Beltramello, Núria Bargalló, Antonio Ferretti, Massimo Caulo, Marco Aiello, Carlo Cavaliere, Andrea Soricelli, Lucilla Parnetti, Roberto Tarducci, Piero Floridi, Magda Tsolaki, Manos Constantinidis, Antonios Drevelegas, Paolo Maria Rossini, Camillo Marra, Peter Schönknecht, Tilman Hensch, Karl Titus Hoffmann, Joost P. Kuijer, Pieter Jelle Visser, Frederik Barkhof, Giovanni B. Frisoni, Jorge Jovicich

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Understanding how to reduce the influence of physiological noise in resting state fMRI data is important for the interpretation of functional brain connectivity. Limited data is currently available to assess the performance of physiological noise correction techniques, in particular when evaluating longitudinal changes in the default mode network (DMN) of healthy elderly participants. In this 3T harmonized multisite fMRI study, we investigated how different retrospective physiological noise correction (rPNC) methods influence the within-site test-retest reliability and the across-site reproducibility consistency of DMN-derived measurements across 13 MRI sites. Elderly participants were scanned twice at least a week apart (five participants per site). The rPNC methods were: none (NPC), Tissue-based regression, PESTICA and FSL-FIX. The DMN at the single subject level was robustly identified using ICA methods in all rPNC conditions. The methods significantly affected the mean z-scores and, albeit less markedly, the cluster-size in the DMN; in particular, FSL-FIX tended to increase the DMN z-scores compared to others. Within-site test-retest reliability was consistent across sites, with no differences across rPNC methods. The absolute percent errors were in the range of 5-11% for DMN z-scores and cluster-size reliability. DMN pattern overlap was in the range 60-65%. In particular, no rPNC method showed a significant reliability improvement relative to NPC. However, FSL-FIX and Tissue-based physiological correction methods showed both similar and significant improvements of reproducibility consistency across the consortium (ICC=0.67) for the DMN z-scores relative to NPC. Overall these findings support the use of rPNC methods like tissue-based or FSL-FIX to characterize multisite longitudinal changes of intrinsic functional connectivity. Hum Brain Mapp 37:2114-2132, 2016.

Original languageEnglish
Pages (from-to)2114-2132
Number of pages19
JournalHuman Brain Mapping
Volume37
Issue number6
DOIs
Publication statusPublished - Jun 1 2016

Fingerprint

Reproducibility of Results
Noise
Magnetic Resonance Imaging
Brain
Healthy Volunteers

Keywords

  • Default mode network
  • Independent component analysis
  • Multisite
  • Physiological noise correction
  • Resting-state networks
  • Task-free fMRI
  • Test-retest reliability

ASJC Scopus subject areas

  • Clinical Neurology
  • Anatomy
  • Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Test-retest reliability of the default mode network in a multi-centric fMRI study of healthy elderly : Effects of data-driven physiological noise correction techniques. / Marchitelli, Rocco; Minati, Ludovico; Marizzoni, Moira; Bosch, Beatriz; Bartrés-Faz, David; Müller, Bernhard W.; Wiltfang, Jens; Fiedler, Ute; Roccatagliata, Luca; Picco, Agnese; Nobili, Flavio; Blin, Oliver; Bombois, Stephanie; Lopes, Renaud; Bordet, Régis; Sein, Julien; Ranjeva, Jean Philippe; Didic, Mira; Gros-Dagnac, Hélène; Payoux, Pierre; Zoccatelli, Giada; Alessandrini, Franco; Beltramello, Alberto; Bargalló, Núria; Ferretti, Antonio; Caulo, Massimo; Aiello, Marco; Cavaliere, Carlo; Soricelli, Andrea; Parnetti, Lucilla; Tarducci, Roberto; Floridi, Piero; Tsolaki, Magda; Constantinidis, Manos; Drevelegas, Antonios; Rossini, Paolo Maria; Marra, Camillo; Schönknecht, Peter; Hensch, Tilman; Hoffmann, Karl Titus; Kuijer, Joost P.; Visser, Pieter Jelle; Barkhof, Frederik; Frisoni, Giovanni B.; Jovicich, Jorge.

In: Human Brain Mapping, Vol. 37, No. 6, 01.06.2016, p. 2114-2132.

Research output: Contribution to journalArticle

Marchitelli, R, Minati, L, Marizzoni, M, Bosch, B, Bartrés-Faz, D, Müller, BW, Wiltfang, J, Fiedler, U, Roccatagliata, L, Picco, A, Nobili, F, Blin, O, Bombois, S, Lopes, R, Bordet, R, Sein, J, Ranjeva, JP, Didic, M, Gros-Dagnac, H, Payoux, P, Zoccatelli, G, Alessandrini, F, Beltramello, A, Bargalló, N, Ferretti, A, Caulo, M, Aiello, M, Cavaliere, C, Soricelli, A, Parnetti, L, Tarducci, R, Floridi, P, Tsolaki, M, Constantinidis, M, Drevelegas, A, Rossini, PM, Marra, C, Schönknecht, P, Hensch, T, Hoffmann, KT, Kuijer, JP, Visser, PJ, Barkhof, F, Frisoni, GB & Jovicich, J 2016, 'Test-retest reliability of the default mode network in a multi-centric fMRI study of healthy elderly: Effects of data-driven physiological noise correction techniques', Human Brain Mapping, vol. 37, no. 6, pp. 2114-2132. https://doi.org/10.1002/hbm.23157
Marchitelli, Rocco ; Minati, Ludovico ; Marizzoni, Moira ; Bosch, Beatriz ; Bartrés-Faz, David ; Müller, Bernhard W. ; Wiltfang, Jens ; Fiedler, Ute ; Roccatagliata, Luca ; Picco, Agnese ; Nobili, Flavio ; Blin, Oliver ; Bombois, Stephanie ; Lopes, Renaud ; Bordet, Régis ; Sein, Julien ; Ranjeva, Jean Philippe ; Didic, Mira ; Gros-Dagnac, Hélène ; Payoux, Pierre ; Zoccatelli, Giada ; Alessandrini, Franco ; Beltramello, Alberto ; Bargalló, Núria ; Ferretti, Antonio ; Caulo, Massimo ; Aiello, Marco ; Cavaliere, Carlo ; Soricelli, Andrea ; Parnetti, Lucilla ; Tarducci, Roberto ; Floridi, Piero ; Tsolaki, Magda ; Constantinidis, Manos ; Drevelegas, Antonios ; Rossini, Paolo Maria ; Marra, Camillo ; Schönknecht, Peter ; Hensch, Tilman ; Hoffmann, Karl Titus ; Kuijer, Joost P. ; Visser, Pieter Jelle ; Barkhof, Frederik ; Frisoni, Giovanni B. ; Jovicich, Jorge. / Test-retest reliability of the default mode network in a multi-centric fMRI study of healthy elderly : Effects of data-driven physiological noise correction techniques. In: Human Brain Mapping. 2016 ; Vol. 37, No. 6. pp. 2114-2132.
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T2 - Effects of data-driven physiological noise correction techniques

AU - Marchitelli, Rocco

AU - Minati, Ludovico

AU - Marizzoni, Moira

AU - Bosch, Beatriz

AU - Bartrés-Faz, David

AU - Müller, Bernhard W.

AU - Wiltfang, Jens

AU - Fiedler, Ute

AU - Roccatagliata, Luca

AU - Picco, Agnese

AU - Nobili, Flavio

AU - Blin, Oliver

AU - Bombois, Stephanie

AU - Lopes, Renaud

AU - Bordet, Régis

AU - Sein, Julien

AU - Ranjeva, Jean Philippe

AU - Didic, Mira

AU - Gros-Dagnac, Hélène

AU - Payoux, Pierre

AU - Zoccatelli, Giada

AU - Alessandrini, Franco

AU - Beltramello, Alberto

AU - Bargalló, Núria

AU - Ferretti, Antonio

AU - Caulo, Massimo

AU - Aiello, Marco

AU - Cavaliere, Carlo

AU - Soricelli, Andrea

AU - Parnetti, Lucilla

AU - Tarducci, Roberto

AU - Floridi, Piero

AU - Tsolaki, Magda

AU - Constantinidis, Manos

AU - Drevelegas, Antonios

AU - Rossini, Paolo Maria

AU - Marra, Camillo

AU - Schönknecht, Peter

AU - Hensch, Tilman

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AU - Kuijer, Joost P.

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KW - Independent component analysis

KW - Multisite

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KW - Resting-state networks

KW - Task-free fMRI

KW - Test-retest reliability

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