Tethered cord: natural history, surgical outcome and risk for Chiari malformation 1 (CM1) - A review of 110 detethering

Laura Grazia Valentini, Giorgio Selvaggio, Sergio Visintini, Alessandra Erbetta, Vidmer Scaioli, Carlo Lazzaro Solero

Research output: Contribution to journalArticle

Abstract

The surgical results of this series of occult spina bifida seem better than the natural history registered in the long pre-operative period in terms of neurological deterioration. The major contribution to this result is attributed to neurophysiological monitoring that lowers the risks of permanent damage and increases the percentage of effective detethering. The present series of TCS, due to conus and filar lipoma, documents that CM1 is a really rare association occurring in less than 6% of the patients, despite the low position of conus. The detethering procedure did not influence the tonsillar position, thus excluding the correlation between the tethering and the tonsillar descent. The genetic alteration documented in a girl reinforces the hypothesis of a rare complex polymaformative picture deserving multiple procedures according to the prevailing clinical symptoms.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalNeurological Sciences
DOIs
Publication statusAccepted/In press - 2011

Fingerprint

Natural History
Neurophysiological Monitoring
Spina Bifida Occulta
Lipoma

Keywords

  • Chiari 1 malformation
  • Children
  • Detethering
  • Tethered cord

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

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abstract = "The surgical results of this series of occult spina bifida seem better than the natural history registered in the long pre-operative period in terms of neurological deterioration. The major contribution to this result is attributed to neurophysiological monitoring that lowers the risks of permanent damage and increases the percentage of effective detethering. The present series of TCS, due to conus and filar lipoma, documents that CM1 is a really rare association occurring in less than 6{\%} of the patients, despite the low position of conus. The detethering procedure did not influence the tonsillar position, thus excluding the correlation between the tethering and the tonsillar descent. The genetic alteration documented in a girl reinforces the hypothesis of a rare complex polymaformative picture deserving multiple procedures according to the prevailing clinical symptoms.",
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AU - Visintini, Sergio

AU - Erbetta, Alessandra

AU - Scaioli, Vidmer

AU - Solero, Carlo Lazzaro

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