Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: A case report

Leonilda Bilo, Roberta Meo, Maria Fulvia de Leva, Caterina Vicidomini, Marco Salvatore, Sabina Pappatà

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the ictal [18F]FDG-PET study of a case of absence status showing bilateral thalamic hypermetabolism and frontal cortex hypometabolism. This is the first ictal assessment of absence status by [18F]FDG-PET reporting this particular cortical and subcortical involvement. Our findings support the theory of corticothalamic circuitry involvement in the pathophysiology of absence seizures and stress the similarities of the clinical and metabolic pattern observed during absences with the pattern of task-induced interruption of the default state of brain function.

Original languageEnglish
Pages (from-to)198-201
Number of pages4
JournalSeizure
Volume19
Issue number3
DOIs
Publication statusPublished - Apr 2010

Keywords

  • Absence status epilepticus
  • Default state
  • Epilepsy
  • FDG-PET study

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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