Thalidomide and thrombosis in patients with multiple myeloma

L. Camba; J. Peccatori; A. Pescarollo; M. Tresoldi; P. Corradini; M. Bregni

Thalidomide and thrombosis in patients with multiple myeloma

L. Camba, J. Peccatori, A. Pescarollo, M. Tresoldi, P. Corradini, M. Bregni

Research output: Contribution to journal › Article › peer-review

Abstract

Thalidomide has recently been employed as a single agent and in combination chemotherapy for experimental treatment relapsed or refractory multiple myeloma and as a first line treatment. A new complication has emerged: a thalidomide-induced hypercoagulable state. We report on 5 patients who developed deep vein thrombosis of the lower limbs while on thalidomide and chemotherapy. The biological mechanism underlying this complication is unknown and appears to be worsened by the association with dexamethasone and/or chemotherapy.

Original language	English
Pages (from-to)	1108-1109
Number of pages	2
Journal	Haematologica
Volume	86
Issue number	10
Publication status	Published - 2001

Keywords

Multiple myeloma
Thalidomide
Thrombosis

ASJC Scopus subject areas

Hematology

Fingerprint Dive into the research topics of 'Thalidomide and thrombosis in patients with multiple myeloma'. Together they form a unique fingerprint.

Cite this

@article{98a40081db5c447d9a4942ca3a6655f8,

title = "Thalidomide and thrombosis in patients with multiple myeloma",

abstract = "Thalidomide has recently been employed as a single agent and in combination chemotherapy for experimental treatment relapsed or refractory multiple myeloma and as a first line treatment. A new complication has emerged: a thalidomide-induced hypercoagulable state. We report on 5 patients who developed deep vein thrombosis of the lower limbs while on thalidomide and chemotherapy. The biological mechanism underlying this complication is unknown and appears to be worsened by the association with dexamethasone and/or chemotherapy.",

keywords = "Multiple myeloma, Thalidomide, Thrombosis",

author = "L. Camba and J. Peccatori and A. Pescarollo and M. Tresoldi and P. Corradini and M. Bregni",

year = "2001",

language = "English",

volume = "86",

pages = "1108--1109",

journal = "Haematologica",

issn = "0390-6078",

publisher = "NLM (Medline)",

number = "10",

}

TY - JOUR

T1 - Thalidomide and thrombosis in patients with multiple myeloma

AU - Camba, L.

AU - Peccatori, J.

AU - Pescarollo, A.

AU - Tresoldi, M.

AU - Corradini, P.

AU - Bregni, M.

PY - 2001

Y1 - 2001

N2 - Thalidomide has recently been employed as a single agent and in combination chemotherapy for experimental treatment relapsed or refractory multiple myeloma and as a first line treatment. A new complication has emerged: a thalidomide-induced hypercoagulable state. We report on 5 patients who developed deep vein thrombosis of the lower limbs while on thalidomide and chemotherapy. The biological mechanism underlying this complication is unknown and appears to be worsened by the association with dexamethasone and/or chemotherapy.

AB - Thalidomide has recently been employed as a single agent and in combination chemotherapy for experimental treatment relapsed or refractory multiple myeloma and as a first line treatment. A new complication has emerged: a thalidomide-induced hypercoagulable state. We report on 5 patients who developed deep vein thrombosis of the lower limbs while on thalidomide and chemotherapy. The biological mechanism underlying this complication is unknown and appears to be worsened by the association with dexamethasone and/or chemotherapy.

KW - Multiple myeloma

KW - Thalidomide

KW - Thrombosis

UR - http://www.scopus.com/inward/record.url?scp=0034766028&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034766028&partnerID=8YFLogxK

M3 - Article

C2 - 11602422

AN - SCOPUS:0034766028

VL - 86

SP - 1108

EP - 1109

JO - Haematologica

JF - Haematologica

SN - 0390-6078

IS - 10

ER -