Thalidomide effectiveness for bilateral chronic idiopathic anterior uveitis in a three-year-old child

Fulvio Parentin, Stefano Da Pozzo, Loredana Lepore, Paolo Perissutti

Research output: Contribution to journalArticle

Abstract

The authors report their experience with thalidomide in the treatment of a bilateral chronic idiopathic uveitis, in a 3-year-old female. This case was complicated by the presence of a cataract and an iris neovascularization in the right eye; furthermore it was partially unresponsive to a conventional anti-inflammatory and immunosuppressive therapy. Oral thalidomide induced slow but dramatic regression of the inflammation, and a significant reabsorption of neovascular tufts, both in slitlamp examination and on iris fluorescein angiography. The authors emphasize the efficacy of thalidomide as anti-inflammatory agent and as inhibitor of neoangiogenesis, reporting the recent literature about the use of this drug in ophthalmology.

Original languageEnglish
Pages (from-to)70-73
Number of pages4
JournalOphthalmologica
Volume215
Issue number1
DOIs
Publication statusPublished - 2001

Fingerprint

Anterior Uveitis
Thalidomide
Iris
Anti-Inflammatory Agents
Fluorescein Angiography
Uveitis
Ophthalmology
Immunosuppressive Agents
Cataract
Inflammation
Therapeutics
Pharmaceutical Preparations

Keywords

  • Children
  • Thalidomide
  • Uveitis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Thalidomide effectiveness for bilateral chronic idiopathic anterior uveitis in a three-year-old child. / Parentin, Fulvio; Da Pozzo, Stefano; Lepore, Loredana; Perissutti, Paolo.

In: Ophthalmologica, Vol. 215, No. 1, 2001, p. 70-73.

Research output: Contribution to journalArticle

Parentin, Fulvio ; Da Pozzo, Stefano ; Lepore, Loredana ; Perissutti, Paolo. / Thalidomide effectiveness for bilateral chronic idiopathic anterior uveitis in a three-year-old child. In: Ophthalmologica. 2001 ; Vol. 215, No. 1. pp. 70-73.
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