Abstract
The authors report their experience with thalidomide in the treatment of a bilateral chronic idiopathic uveitis, in a 3-year-old female. This case was complicated by the presence of a cataract and an iris neovascularization in the right eye; furthermore it was partially unresponsive to a conventional anti-inflammatory and immunosuppressive therapy. Oral thalidomide induced slow but dramatic regression of the inflammation, and a significant reabsorption of neovascular tufts, both in slitlamp examination and on iris fluorescein angiography. The authors emphasize the efficacy of thalidomide as anti-inflammatory agent and as inhibitor of neoangiogenesis, reporting the recent literature about the use of this drug in ophthalmology.
| Original language | English |
|---|---|
| Pages (from-to) | 70-73 |
| Number of pages | 4 |
| Journal | Ophthalmologica |
| Volume | 215 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2001 |
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Keywords
- Children
- Thalidomide
- Uveitis
ASJC Scopus subject areas
- Ophthalmology
Cite this
Thalidomide effectiveness for bilateral chronic idiopathic anterior uveitis in a three-year-old child. / Parentin, Fulvio; Da Pozzo, Stefano; Lepore, Loredana; Perissutti, Paolo.
In: Ophthalmologica, Vol. 215, No. 1, 2001, p. 70-73.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Thalidomide effectiveness for bilateral chronic idiopathic anterior uveitis in a three-year-old child
AU - Parentin, Fulvio
AU - Da Pozzo, Stefano
AU - Lepore, Loredana
AU - Perissutti, Paolo
PY - 2001
Y1 - 2001
N2 - The authors report their experience with thalidomide in the treatment of a bilateral chronic idiopathic uveitis, in a 3-year-old female. This case was complicated by the presence of a cataract and an iris neovascularization in the right eye; furthermore it was partially unresponsive to a conventional anti-inflammatory and immunosuppressive therapy. Oral thalidomide induced slow but dramatic regression of the inflammation, and a significant reabsorption of neovascular tufts, both in slitlamp examination and on iris fluorescein angiography. The authors emphasize the efficacy of thalidomide as anti-inflammatory agent and as inhibitor of neoangiogenesis, reporting the recent literature about the use of this drug in ophthalmology.
AB - The authors report their experience with thalidomide in the treatment of a bilateral chronic idiopathic uveitis, in a 3-year-old female. This case was complicated by the presence of a cataract and an iris neovascularization in the right eye; furthermore it was partially unresponsive to a conventional anti-inflammatory and immunosuppressive therapy. Oral thalidomide induced slow but dramatic regression of the inflammation, and a significant reabsorption of neovascular tufts, both in slitlamp examination and on iris fluorescein angiography. The authors emphasize the efficacy of thalidomide as anti-inflammatory agent and as inhibitor of neoangiogenesis, reporting the recent literature about the use of this drug in ophthalmology.
KW - Children
KW - Thalidomide
KW - Uveitis
UR - http://www.scopus.com/inward/record.url?scp=0035189281&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035189281&partnerID=8YFLogxK
U2 - 10.1159/000050830
DO - 10.1159/000050830
M3 - Article
C2 - 11125274
AN - SCOPUS:0035189281
VL - 215
SP - 70
EP - 73
JO - Ophthalmologica
JF - Ophthalmologica
SN - 0030-3755
IS - 1
ER -