The ΔF508 mutation in cystic fibrosis patients of Southern Italy

Gianfranco Sebastio, Ornella Castiglione, Barbara Incerti, Donatello Salvatore, Francesca Santamaria

Research output: Contribution to journalArticlepeer-review

Abstract

Fifty one independent cystic fibrosis (CF) families originating from a restricted area of Southern Italy (Campania) have been analyzed for KM19 and XV2c haplotypes and the ΔF508 mutation: 54% of the total CF chromosomes show the ΔF508 mutation. No significative correlations were obtained when clinical score, radiological score, Pseudomonas colonization, or clinical symptoms at presentation were matched with the presence or absence of the ΔF508 mutation.

Original languageEnglish
Pages (from-to)430-431
Number of pages2
JournalHuman Genetics
Volume85
Issue number4
DOIs
Publication statusPublished - Sep 1990

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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