TY - JOUR
T1 - The ΔF508 mutation in cystic fibrosis patients of Southern Italy
AU - Sebastio, Gianfranco
AU - Castiglione, Ornella
AU - Incerti, Barbara
AU - Salvatore, Donatello
AU - Santamaria, Francesca
PY - 1990/9
Y1 - 1990/9
N2 - Fifty one independent cystic fibrosis (CF) families originating from a restricted area of Southern Italy (Campania) have been analyzed for KM19 and XV2c haplotypes and the ΔF508 mutation: 54% of the total CF chromosomes show the ΔF508 mutation. No significative correlations were obtained when clinical score, radiological score, Pseudomonas colonization, or clinical symptoms at presentation were matched with the presence or absence of the ΔF508 mutation.
AB - Fifty one independent cystic fibrosis (CF) families originating from a restricted area of Southern Italy (Campania) have been analyzed for KM19 and XV2c haplotypes and the ΔF508 mutation: 54% of the total CF chromosomes show the ΔF508 mutation. No significative correlations were obtained when clinical score, radiological score, Pseudomonas colonization, or clinical symptoms at presentation were matched with the presence or absence of the ΔF508 mutation.
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U2 - 10.1007/BF02428299
DO - 10.1007/BF02428299
M3 - Article
C2 - 2210764
AN - SCOPUS:0025186297
VL - 85
SP - 430
EP - 431
JO - Human Genetics
JF - Human Genetics
SN - 0340-6717
IS - 4
ER -