The 2020 Italian Society of Arterial Hypertension (SIIA) practical guidelines for the management of primary aldosteronism

Gian Paolo Rossi, Valeria Bisogni, Alessandra Violet Bacca, Anna Belfiore, Maurizio Cesari, Antonio Concistrè, Rita Del Pinto, Bruno Fabris, Francesco Fallo, Cristiano Fava, Claudio Ferri, Gilberta Giacchetti, Guido Grassi, Claudio Letizia, Mauro Maccario, Francesca Mallamaci, Giuseppe Maiolino, Dario Manfellotto, Pietro Minuz, Silvia MonticoneAlberto Morganti, Maria Lorenza Muiesan, Paolo Mulatero, Aurelio Negro, Gianfranco Parati, Martino F Pengo, Luigi Petramala, Francesca Pizzolo, Damiano Rizzoni, Giacomo Rossitto, Franco Veglio, Teresa Maria Seccia

Research output: Contribution to journalReview articlepeer-review


Background and aim: Considering the amount of novel knowledge generated in the last five years, a team of experienced hypertensionlogists was assembled to furnish updated clinical practice guidelines for the management of primary aldosteronism.

Methods: To identify the most relevant studies, the authors utilized a systematic literature review in international databases by applying the PICO strategy, and then they were required to make use of only those meeting predefined quality criteria. For studies of diagnostic tests, only those that fulfilled the Standards for Reporting of Diagnostic Accuracy recommendations were considered.

Results: Each section was jointly prepared by at least two co-authors, who provided Class of Recommendation and Level of Evidence following the American Heart Association methodology. The guidelines were sponsored by the Italian Society of Arterial Hypertension and underwent two rounds of revision, eventually reexamined by an External Committee. They were presented and thoroughly discussed in two face-to-face meetings with all co-authors and then presented on occasion of the 36th Italian Society of Arterial Hypertension meeting in order to gather further feedbacks by all members. The text amended according to these feedbacks was subjected to a further peer review.

Conclusions: After this process, substantial updated information was generated, which could simplify the diagnosis of primary aldosteronism and assist practicing physicians in optimizing treatment and follow-up of patients with one of the most common curable causes of arterial hypertension.

Original languageEnglish
Pages (from-to)100029
JournalInternational Journal of Cardiology: Hypertension
Publication statusPublished - Jun 2020


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