The 2nd Berlin BedRest study: Protocol and implementation

D. L. Belavý; O. Bock; H. Börst; G. Armbrecht; U. Gast; C. Degner; G. Beller; H. Soll; M. Salanova; H. Habazettl; M. Heer; A. de Haan; D. F. Stegeman; P. Cerretelli; D. Blottner; J. Rittweger; C. Gelfi; U. Kornak; D. Felsenberg

The 2nd Berlin BedRest study: Protocol and implementation

D. L. Belavý, O. Bock, H. Börst, G. Armbrecht, U. Gast, C. Degner, G. Beller, H. Soll, M. Salanova, H. Habazettl, M. Heer, A. de Haan, D. F. Stegeman, P. Cerretelli, D. Blottner, J. Rittweger, C. Gelfi, U. Kornak, D. Felsenberg

IRCCS Policlinico San Donato

Research output: Contribution to journal › Article

Abstract

Long-term bed-rest is used to simulate the effect of spaceflight on the human body and test different kinds of countermeasures. The 2^nd Berlin BedRest Study (BBR2-2) tested the efficacy of whole-body vibration in addition to high-load resisitance exercise in preventing bone loss during bed-rest. Here we present the protocol of the study and discuss its implementation. Twenty-four male subjects underwent 60-days of six-degree head down tilt bed-rest and were randomised to an inactive control group (CTR), a high-load resistive exercise group (RE) or a high-load resistive exercise with whole-body vibration group (RVE). Subsequent to events in the course of the study (e.g. subject withdrawal), 9 subjects participated in the CTR-group, 7 in the RVE-group and 8 (7 beyond bed-rest day-30) in the RE-group. Fluid intake, urine output and axiallary temperature increased during bed-rest (p

Original language	English
Pages (from-to)	207-219
Number of pages	13
Journal	Journal of Musculoskeletal Neuronal Interactions
Volume	10
Issue number	3
Publication status	Published - Sep 2010

Keywords

Countermeasures
Exercise
Inactivity
Microgravity
Spaceflight

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Orthopedics and Sports Medicine
Physiology

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Belavý, D. L., Bock, O., Börst, H., Armbrecht, G., Gast, U., Degner, C., Beller, G., Soll, H., Salanova, M., Habazettl, H., Heer, M., de Haan, A., Stegeman, D. F., Cerretelli, P., Blottner, D., Rittweger, J., Gelfi, C., Kornak, U., & Felsenberg, D. (2010). The 2nd Berlin BedRest study: Protocol and implementation. Journal of Musculoskeletal Neuronal Interactions, 10(3), 207-219.

The 2nd Berlin BedRest study : Protocol and implementation. / Belavý, D. L.; Bock, O.; Börst, H.; Armbrecht, G.; Gast, U.; Degner, C.; Beller, G.; Soll, H.; Salanova, M.; Habazettl, H.; Heer, M.; de Haan, A.; Stegeman, D. F.; Cerretelli, P.; Blottner, D.; Rittweger, J.; Gelfi, C.; Kornak, U.; Felsenberg, D.

In: Journal of Musculoskeletal Neuronal Interactions, Vol. 10, No. 3, 09.2010, p. 207-219.

Research output: Contribution to journal › Article

Belavý, DL, Bock, O, Börst, H, Armbrecht, G, Gast, U, Degner, C, Beller, G, Soll, H, Salanova, M, Habazettl, H, Heer, M, de Haan, A, Stegeman, DF, Cerretelli, P, Blottner, D, Rittweger, J, Gelfi, C, Kornak, U & Felsenberg, D 2010, 'The 2nd Berlin BedRest study: Protocol and implementation', Journal of Musculoskeletal Neuronal Interactions, vol. 10, no. 3, pp. 207-219.

Belavý, D. L. ; Bock, O. ; Börst, H. ; Armbrecht, G. ; Gast, U. ; Degner, C. ; Beller, G. ; Soll, H. ; Salanova, M. ; Habazettl, H. ; Heer, M. ; de Haan, A. ; Stegeman, D. F. ; Cerretelli, P. ; Blottner, D. ; Rittweger, J. ; Gelfi, C. ; Kornak, U. ; Felsenberg, D. / The 2nd Berlin BedRest study : Protocol and implementation. In: Journal of Musculoskeletal Neuronal Interactions. 2010 ; Vol. 10, No. 3. pp. 207-219.

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