The accuracy of noninvasive methods in the prediction of clinically relevant outcomes in patients with chronic liver disease

Mirella Fraquelli, Roberta Pozzi

Research output: Contribution to journalArticle

Abstract

Evaluation of: Chon YE, Jung ES, Park JY et al. The accuracy of noninvasive methods in predicting the development of hepatocellular carcinoma and hepatic decompensation in patients with chronic hepatitis B. J. Clin. Gastroenterol. 46(6), 518-525 (2012). The prognosis of chronic liver diseases, which represent a major public health problem, is mainly linked to the extent and progression of liver fibrosis and the subsequent risk of developing cirrhosis and related complications, mainly hepatocellular carcinoma. The article reviewed here reports on the prognostic role of liver stiffness as measured by transient elastography and other noninvasive methods in the prediction of clinical decompensation and hepatocellular carcinoma in patients with chronic hepatitis B. From the results of the study, liver stiffness measurement, as obtained using transient elastography and other noninvasive tests used to assess liver fibrosis, can accurately predict the development of hepatocellular carcinoma and variceal bleeding in patients with chronic hepatitis B.

Original languageEnglish
Pages (from-to)679-682
Number of pages4
JournalExpert Review of Gastroenterology and Hepatology
Volume6
Issue number6
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Liver Diseases
Hepatocellular Carcinoma
Chronic Hepatitis B
Chronic Disease
Elasticity Imaging Techniques
Liver Cirrhosis
Liver
Fibrosis
Public Health
Hemorrhage

Keywords

  • chronic hepatitis B
  • fibroscan
  • HCC
  • hepatic fibrosis
  • liver biopsy
  • transient elastography

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

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abstract = "Evaluation of: Chon YE, Jung ES, Park JY et al. The accuracy of noninvasive methods in predicting the development of hepatocellular carcinoma and hepatic decompensation in patients with chronic hepatitis B. J. Clin. Gastroenterol. 46(6), 518-525 (2012). The prognosis of chronic liver diseases, which represent a major public health problem, is mainly linked to the extent and progression of liver fibrosis and the subsequent risk of developing cirrhosis and related complications, mainly hepatocellular carcinoma. The article reviewed here reports on the prognostic role of liver stiffness as measured by transient elastography and other noninvasive methods in the prediction of clinical decompensation and hepatocellular carcinoma in patients with chronic hepatitis B. From the results of the study, liver stiffness measurement, as obtained using transient elastography and other noninvasive tests used to assess liver fibrosis, can accurately predict the development of hepatocellular carcinoma and variceal bleeding in patients with chronic hepatitis B.",
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