Abstract
Introduction: RECIPE study was designed to assess the impact of dietary supplementation with fermented milk enriched with plant sterols (FMPS) on the nutritional behavior, lifestyle and the joint therapeutic responsibility of hypercholesterolemic patients. Methods: Observational, prospective, multicenter, international study, was conducted to assess dietary habits and other lifestyle components in hypercholesterolemic patients in whom the general practitioner indicated FMPS supplementation. Nutritional, lifestyle and clinical data were collected at the initial visit and after a 4 months follow-up. The biochemical and anthropometric data were retrieved from medical records obtained at baseline and 4 months. Results: We report the results of Spain. Two hundred and one physicians who provided valid data of 1044 patients participated. The addition of FMPS was associated with improved overall nutritional index, being adequate initially in 28.2% of patients, and increasing up to 75.2% at the end of the study (P<001). This nutritional change was associated with an improvement in the lipid profile and anthropometric data. Patients more adherent to therapy generally achieved a better result in all parameters compared to non-compliant ones. Conclusions: The addition of FMPS to a diet designed to reduce the LDL enhances the patient's attitude regarding changes in lifestyle, leading to better overall control of dyslipidemia and anthropometric improvement.
| Translated title of the contribution | The addition of fermented milk with plant sterols improves the adherence to lifestyle changes in hypercholesterolemic patients. The RECIPE study |
|---|---|
| Original language | Spanish |
| Pages (from-to) | 173-180 |
| Number of pages | 8 |
| Journal | Clinica e Investigacion en Arteriosclerosis |
| Volume | 24 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jul 2012 |
Keywords
- Diet
- Fermented milk
- Hypercholesterolemia
- Lifestyle
- Phytosterol
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Pharmacology (medical)
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La adición de leche fermentada suplementada con esteroles vegetales mejora el cumplimiento de los cambios en el estilo de vida en los pacientes hipercolesterolémicos. Estudio RECIPE. / Masana, Lluís; Lagares, Manuel; Pintó, Xavier; Reinares, Leandro; Zúñiga, Manuel; Descamps, Olivier; Bosi, Emanuele; Allaert, François Andrè; Chapman, John; Bruckert, Erik; Hernandez, T.; Martin, C.; Gomes, H.; Perez, P. J.; Gil, E. M.; Moro, A.; Jorda, M. D.; Lopez, J. L.; Alba, M.; Bilbao, I.; Alustiza, M. R.; Aliaga, M.; Muñoz, J. G.; Terol, A. M.; Gomez, P.; Marcos, M. A.; Gonzalez, M.; Rodriguez, M. J.; Lopez, M. V.; Romero, M. A.; Puyo, N.; Egido, J. F.; Monreal, I.; Ramirez, A.; Madariaga, M. A.; De Miguel, M. C.; Lorda, A.; Muñoz, G.; Moreno, I. M.; Martinez, A.; Sanchez, A.; Espino, A.; Gonzalez., F. J.; Pracht, C.; Ocaña, C.; Pena, M. A.; Domingo, C.; Gilaberte, M. T.; Garcia, C.; Diez, J. A.; Fornes, F. V.; Gutierrez, M. D.; Macarra, E.; Bugella, J. I.; Del.J., M.; Bravo, A.; Becerra, M. J.; Carbonell, C.; De Miguel, M.; Perez, A.; Martin, A.; Perez, A.; Romero, J.; Gonzalez, P.; Iglesias, A.; Lopez, B.; Villalonga, G.; Carvajal, P.; Marin, C.; Cardona, F.; Gonzalez, A.; Fernandez, G.; Gomez, D.; Sanchez, C. L.; Viveros, D.; De Lucas, M. G.; Marin, J. M.; Osorno, J.; Pumares, C.; Gimenez, R.; Latorre, J.; Barreiro, M. C.; Villanueva, J. R.; Lopez, J. A.; Balaguer, I.; Baron, J.; Espuga, M.; Firas, R.; Trias, F.; Moran, A.; Velasco, V.; Vazquez, F.; Hernando, A.; Manzanares, A.; Abad, J. L.; Peraferrer, M.; Obarrio, A.; Alonso, M. L.; Gomez, L.; Roca, J.; Ayus, B. E.; Urban, F.; Gonzalez, E.; Masegosa, C.; Barrilero, E.; Jimenez, M. C.; Carratala, M. M.; Petitbo, D.; Ferrandiz, J.; Mialdea, M. J.; Montoro, J.; Muncharaz, M. E.; Rodriguez, M. J.; Shehchar, A.; De Paula, L.; Cano, A.; Sanchez, L.; Perez, J.; Alarcon, C.; Martinez, J. F.; Garrido, T.; Martinez, F.; Gomariz, I.; Caparros, M.; Perez, A.; Kseibi, T.; Palomo, L.; Jimenez, T.; Luque, I.; Villar, P.; Gonzalez, J. J.; Aparicio, J.; Jimenez, O.; Muñoz, J. J.; Baez, F.; Sanchez, A.; Marcos, M. P.; Gonzalez, T.; Estevez, J. A.; Perez, A.; Garcia, J.; Ajuria-Gogeasko, S.; Cabrera, M.; Manzano, J. M.; Segura, G.; Abat, X.; Yanovsky, N.; Borrachero, J. M.; Fortuny, M.; Martinez, M. D.; Gutierrez, A. R.; Najem, N.; Romero, M. C.; Martin, S.; Valverde, R. J.; Molina, C.; Martinez, B.; Izquierdo, L.; Vazquez, I.; Martinez, M. T.; Mateos, A.; Quiles, F.; Aranda, F. J.; Iborra, R.; Valero, A. B.; Fornes, M. T.; Quinza, V.; Colado, F.; Arribas, B.; Martinez, J. E L; Garces, M. P.; Valero, J. M.; Frigola, J. L.; Rubio, J. M.; Gongora, A.; Triana, J.; Gomez, C.; Garcia, M. L.; Diez, C.; Pombo, G.; Gutierrez, M. C.; Nazara, C. A.; De Oca, M. A.; Maquieira, N.; Pilo, A.; Buenadicha, J. L.; Duran, F.; Peña, J. E.; Navarro, S.; Serrano, F. J.; Sanchez, S.; Mesa, S.; Salazar, J. A.; De La Escosura, A.; Perez, F.; Solera, J.; Tarraga, P.; Ramos, L.; Gutierrez, J. A.; Caldelas, S.; Albiñana, F.; Lopez, J. F.; Florian, J.; Rocha, E.; Rodriguez, J.; Mellado, M. L.; Calvillo, M. R.; Cruz, T.; Capitan, M.; Diaz, J.; Tome, J.; Prieto, A.; Tome, V.; Caro, M.; Montero, A.; Ontoria, M.; Garcia, D. L.; Gil, F.; De Zarate, V.; Gonzalez, A.; Baron, J.; Casaponsa, J.; Matamala, J.; Salvande, A.; Trueba, M. A.; Cidra, J. L.; Garcia, A.; Toro, A.; Berna, J. R.; Zornoza, B.; Prieto, M. T.; Garcia, L.; Lopez, C.; Garcia, P.; Echegaray, M. C.; Navarro, B.; Moro, M. L.; Herrero, A.; Tamargo, C.; Perez, S. J.; Antero, E.; Penacho, M. C.; Blanco, Y.; Lucena, J.; Sisto, C. A.; Salido, E.; Dolz, F.; Granja, J. M.; Saavedra, F.; Sanchez-Oro, I.; Mas-Magro, F.; Artundo, T.; Fernandez, A.; Vaquer, J. V.; Aso, K.; Palacios, A.; Morante, J. L.; Seller, T.; Vendrell, J. M.
In: Clinica e Investigacion en Arteriosclerosis, Vol. 24, No. 4, 07.2012, p. 173-180.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - La adición de leche fermentada suplementada con esteroles vegetales mejora el cumplimiento de los cambios en el estilo de vida en los pacientes hipercolesterolémicos. Estudio RECIPE
AU - Masana, Lluís
AU - Lagares, Manuel
AU - Pintó, Xavier
AU - Reinares, Leandro
AU - Zúñiga, Manuel
AU - Descamps, Olivier
AU - Bosi, Emanuele
AU - Allaert, François Andrè
AU - Chapman, John
AU - Bruckert, Erik
AU - Hernandez, T.
AU - Martin, C.
AU - Gomes, H.
AU - Perez, P. J.
AU - Gil, E. M.
AU - Moro, A.
AU - Jorda, M. D.
AU - Lopez, J. L.
AU - Alba, M.
AU - Bilbao, I.
AU - Alustiza, M. R.
AU - Aliaga, M.
AU - Muñoz, J. G.
AU - Terol, A. M.
AU - Gomez, P.
AU - Marcos, M. A.
AU - Gonzalez, M.
AU - Rodriguez, M. J.
AU - Lopez, M. V.
AU - Romero, M. A.
AU - Puyo, N.
AU - Egido, J. F.
AU - Monreal, I.
AU - Ramirez, A.
AU - Madariaga, M. A.
AU - De Miguel, M. C.
AU - Lorda, A.
AU - Muñoz, G.
AU - Moreno, I. M.
AU - Martinez, A.
AU - Sanchez, A.
AU - Espino, A.
AU - Gonzalez., F. J.
AU - Pracht, C.
AU - Ocaña, C.
AU - Pena, M. A.
AU - Domingo, C.
AU - Gilaberte, M. T.
AU - Garcia, C.
AU - Diez, J. A.
AU - Fornes, F. V.
AU - Gutierrez, M. D.
AU - Macarra, E.
AU - Bugella, J. I.
AU - Del.J., M.
AU - Bravo, A.
AU - Becerra, M. J.
AU - Carbonell, C.
AU - De Miguel, M.
AU - Perez, A.
AU - Martin, A.
AU - Perez, A.
AU - Romero, J.
AU - Gonzalez, P.
AU - Iglesias, A.
AU - Lopez, B.
AU - Villalonga, G.
AU - Carvajal, P.
AU - Marin, C.
AU - Cardona, F.
AU - Gonzalez, A.
AU - Fernandez, G.
AU - Gomez, D.
AU - Sanchez, C. L.
AU - Viveros, D.
AU - De Lucas, M. G.
AU - Marin, J. M.
AU - Osorno, J.
AU - Pumares, C.
AU - Gimenez, R.
AU - Latorre, J.
AU - Barreiro, M. C.
AU - Villanueva, J. R.
AU - Lopez, J. A.
AU - Balaguer, I.
AU - Baron, J.
AU - Espuga, M.
AU - Firas, R.
AU - Trias, F.
AU - Moran, A.
AU - Velasco, V.
AU - Vazquez, F.
AU - Hernando, A.
AU - Manzanares, A.
AU - Abad, J. L.
AU - Peraferrer, M.
AU - Obarrio, A.
AU - Alonso, M. L.
AU - Gomez, L.
AU - Roca, J.
AU - Ayus, B. E.
AU - Urban, F.
AU - Gonzalez, E.
AU - Masegosa, C.
AU - Barrilero, E.
AU - Jimenez, M. C.
AU - Carratala, M. M.
AU - Petitbo, D.
AU - Ferrandiz, J.
AU - Mialdea, M. J.
AU - Montoro, J.
AU - Muncharaz, M. E.
AU - Rodriguez, M. J.
AU - Shehchar, A.
AU - De Paula, L.
AU - Cano, A.
AU - Sanchez, L.
AU - Perez, J.
AU - Alarcon, C.
AU - Martinez, J. F.
AU - Garrido, T.
AU - Martinez, F.
AU - Gomariz, I.
AU - Caparros, M.
AU - Perez, A.
AU - Kseibi, T.
AU - Palomo, L.
AU - Jimenez, T.
AU - Luque, I.
AU - Villar, P.
AU - Gonzalez, J. J.
AU - Aparicio, J.
AU - Jimenez, O.
AU - Muñoz, J. J.
AU - Baez, F.
AU - Sanchez, A.
AU - Marcos, M. P.
AU - Gonzalez, T.
AU - Estevez, J. A.
AU - Perez, A.
AU - Garcia, J.
AU - Ajuria-Gogeasko, S.
AU - Cabrera, M.
AU - Manzano, J. M.
AU - Segura, G.
AU - Abat, X.
AU - Yanovsky, N.
AU - Borrachero, J. M.
AU - Fortuny, M.
AU - Martinez, M. D.
AU - Gutierrez, A. R.
AU - Najem, N.
AU - Romero, M. C.
AU - Martin, S.
AU - Valverde, R. J.
AU - Molina, C.
AU - Martinez, B.
AU - Izquierdo, L.
AU - Vazquez, I.
AU - Martinez, M. T.
AU - Mateos, A.
AU - Quiles, F.
AU - Aranda, F. J.
AU - Iborra, R.
AU - Valero, A. B.
AU - Fornes, M. T.
AU - Quinza, V.
AU - Colado, F.
AU - Arribas, B.
AU - Martinez, J. E L
AU - Garces, M. P.
AU - Valero, J. M.
AU - Frigola, J. L.
AU - Rubio, J. M.
AU - Gongora, A.
AU - Triana, J.
AU - Gomez, C.
AU - Garcia, M. L.
AU - Diez, C.
AU - Pombo, G.
AU - Gutierrez, M. C.
AU - Nazara, C. A.
AU - De Oca, M. A.
AU - Maquieira, N.
AU - Pilo, A.
AU - Buenadicha, J. L.
AU - Duran, F.
AU - Peña, J. E.
AU - Navarro, S.
AU - Serrano, F. J.
AU - Sanchez, S.
AU - Mesa, S.
AU - Salazar, J. A.
AU - De La Escosura, A.
AU - Perez, F.
AU - Solera, J.
AU - Tarraga, P.
AU - Ramos, L.
AU - Gutierrez, J. A.
AU - Caldelas, S.
AU - Albiñana, F.
AU - Lopez, J. F.
AU - Florian, J.
AU - Rocha, E.
AU - Rodriguez, J.
AU - Mellado, M. L.
AU - Calvillo, M. R.
AU - Cruz, T.
AU - Capitan, M.
AU - Diaz, J.
AU - Tome, J.
AU - Prieto, A.
AU - Tome, V.
AU - Caro, M.
AU - Montero, A.
AU - Ontoria, M.
AU - Garcia, D. L.
AU - Gil, F.
AU - De Zarate, V.
AU - Gonzalez, A.
AU - Baron, J.
AU - Casaponsa, J.
AU - Matamala, J.
AU - Salvande, A.
AU - Trueba, M. A.
AU - Cidra, J. L.
AU - Garcia, A.
AU - Toro, A.
AU - Berna, J. R.
AU - Zornoza, B.
AU - Prieto, M. T.
AU - Garcia, L.
AU - Lopez, C.
AU - Garcia, P.
AU - Echegaray, M. C.
AU - Navarro, B.
AU - Moro, M. L.
AU - Herrero, A.
AU - Tamargo, C.
AU - Perez, S. J.
AU - Antero, E.
AU - Penacho, M. C.
AU - Blanco, Y.
AU - Lucena, J.
AU - Sisto, C. A.
AU - Salido, E.
AU - Dolz, F.
AU - Granja, J. M.
AU - Saavedra, F.
AU - Sanchez-Oro, I.
AU - Mas-Magro, F.
AU - Artundo, T.
AU - Fernandez, A.
AU - Vaquer, J. V.
AU - Aso, K.
AU - Palacios, A.
AU - Morante, J. L.
AU - Seller, T.
AU - Vendrell, J. M.
PY - 2012/7
Y1 - 2012/7
N2 - Introduction: RECIPE study was designed to assess the impact of dietary supplementation with fermented milk enriched with plant sterols (FMPS) on the nutritional behavior, lifestyle and the joint therapeutic responsibility of hypercholesterolemic patients. Methods: Observational, prospective, multicenter, international study, was conducted to assess dietary habits and other lifestyle components in hypercholesterolemic patients in whom the general practitioner indicated FMPS supplementation. Nutritional, lifestyle and clinical data were collected at the initial visit and after a 4 months follow-up. The biochemical and anthropometric data were retrieved from medical records obtained at baseline and 4 months. Results: We report the results of Spain. Two hundred and one physicians who provided valid data of 1044 patients participated. The addition of FMPS was associated with improved overall nutritional index, being adequate initially in 28.2% of patients, and increasing up to 75.2% at the end of the study (P<001). This nutritional change was associated with an improvement in the lipid profile and anthropometric data. Patients more adherent to therapy generally achieved a better result in all parameters compared to non-compliant ones. Conclusions: The addition of FMPS to a diet designed to reduce the LDL enhances the patient's attitude regarding changes in lifestyle, leading to better overall control of dyslipidemia and anthropometric improvement.
AB - Introduction: RECIPE study was designed to assess the impact of dietary supplementation with fermented milk enriched with plant sterols (FMPS) on the nutritional behavior, lifestyle and the joint therapeutic responsibility of hypercholesterolemic patients. Methods: Observational, prospective, multicenter, international study, was conducted to assess dietary habits and other lifestyle components in hypercholesterolemic patients in whom the general practitioner indicated FMPS supplementation. Nutritional, lifestyle and clinical data were collected at the initial visit and after a 4 months follow-up. The biochemical and anthropometric data were retrieved from medical records obtained at baseline and 4 months. Results: We report the results of Spain. Two hundred and one physicians who provided valid data of 1044 patients participated. The addition of FMPS was associated with improved overall nutritional index, being adequate initially in 28.2% of patients, and increasing up to 75.2% at the end of the study (P<001). This nutritional change was associated with an improvement in the lipid profile and anthropometric data. Patients more adherent to therapy generally achieved a better result in all parameters compared to non-compliant ones. Conclusions: The addition of FMPS to a diet designed to reduce the LDL enhances the patient's attitude regarding changes in lifestyle, leading to better overall control of dyslipidemia and anthropometric improvement.
KW - Diet
KW - Fermented milk
KW - Hypercholesterolemia
KW - Lifestyle
KW - Phytosterol
UR - http://www.scopus.com/inward/record.url?scp=84864305175&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864305175&partnerID=8YFLogxK
U2 - 10.1016/j.arteri.2012.04.004
DO - 10.1016/j.arteri.2012.04.004
M3 - Articolo
AN - SCOPUS:84864305175
VL - 24
SP - 173
EP - 180
JO - Clinica e Investigacion en Arteriosclerosis
JF - Clinica e Investigacion en Arteriosclerosis
SN - 0214-9168
IS - 4
ER -