Il test di alcalinizzazione nella diagnosi di angina spontanea.

Translated title of the contribution: The alkalinization test in the diagnosis of spontaneous angina

M. Ferratini, P. Cerri, S. Pirelli

Research output: Contribution to journalArticlepeer-review


The induction of alkalosis has been proposed as provocative test of coronary spasm in patients affected by vasospastic angina. We submitted to the test 43 patients, affected by angina with a previous documentation of spontaneous ischemia (19 patients with ST elevation and 24 patients with ST depression at the EKG registered during pain). Twelve patients had normal coronary arteries; in 14 patients a significant stenosis of a single vessel was present; in 15 patients 2 vessels were involved and in 2 a 3-vessel disease was demonstrated. The test induced ischemia in 17 patients (39.6%). The positivity of the test was strictly dependent on the period of time elapsed between the last documented crisis of angina and the provocative test: it induced ischemia in 75% of the patients who underwent the test in the acute phase: on the other hand it was constantly negative in patients who had not complained of anginal pain for more than 6 months. In the screening of patients with chest pain at rest, the test of alkalosis does not seem, therefore, useful as a diagnostic tool.

Translated title of the contributionThe alkalinization test in the diagnosis of spontaneous angina
Original languageItalian
Pages (from-to)158-163
Number of pages6
JournalGiornale Italiano di Cardiologia
Issue number3
Publication statusPublished - Mar 1984

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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