Pulmonary development is divided in six stages and ends with the establishment of mature respiratory alveoli necessary for an adequate gas exchange. Surfactant is essential for the development of the functional residual capacity (FRC). Lung fluid balance is regulated by active sodium and chloride transporters (ENaC) across the pulmonary epithelium. Many factors can affect pulmonary maturation and physiology in newborns. Mechanical respiratory support may damage the alveoli through different mechanism, causing the VILI (Ventilator Lung Induced Injury).
|Translated title of the contribution||The alveolus: Novelties in terms of development and function|
|Number of pages||5|
|Publication status||Published - Sep 2011|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health