The antigenic determinant of fibrin(ogen) measured with agglutination inhibition immunoassays

A. Molla, M. B. Donati, J. Vermylen

Research output: Contribution to journalArticle

Abstract

Agglutination inhibition immunoassays using antifibrinogen antiserum measure an antigenic determinant of fibrinogen which is located on fragment D parts of this molecule. This antigenic determinant of fragment D, in contrast to others, does not form an immune precipitate with antifibrinogen antiserum. Upon very extensive hydrolysis by plasmin, this antigenic determinant has a reduced affinity for its antibody.

Original languageEnglish
Pages (from-to)473-479
Number of pages7
JournalJournal of Clinical Pathology
Volume27
Issue number6
Publication statusPublished - 1974

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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