The apelin/APJ system: From vascular biology to heart failure

Pietro Francia, Cristina Balla, Francesco Paneni, Massimo Volpe

Research output: Contribution to journalArticle

Abstract

Apelin, the endogenous ligand of the G protein-coupled APJ receptor, displays several activities on the cardiovascular system. Indeed, recent studies support the notion that the apelin/APJ system is involved in key mechanisms that are relevant to fluid homeostasis, blood pressure control and cardiac contractility. This paper reviews our current knowledge on the physiological properties and potential clinical significance of apelin and APJ receptor.

Original languageEnglish
Pages (from-to)159-162
Number of pages4
JournalHigh Blood Pressure and Cardiovascular Prevention
Volume13
Issue number4
DOIs
Publication statusPublished - 2006

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G-Protein-Coupled Receptors
Cardiovascular System
Blood Vessels
Homeostasis
Heart Failure
Blood Pressure
Ligands

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The apelin/APJ system : From vascular biology to heart failure. / Francia, Pietro; Balla, Cristina; Paneni, Francesco; Volpe, Massimo.

In: High Blood Pressure and Cardiovascular Prevention, Vol. 13, No. 4, 2006, p. 159-162.

Research output: Contribution to journalArticle

Francia, Pietro ; Balla, Cristina ; Paneni, Francesco ; Volpe, Massimo. / The apelin/APJ system : From vascular biology to heart failure. In: High Blood Pressure and Cardiovascular Prevention. 2006 ; Vol. 13, No. 4. pp. 159-162.
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