The association between psychotic experiences and health-related quality of life: a cross-national analysis based on World Mental Health Surveys

WHO World Mental Health Survey Collaborators

Research output: Contribution to journalArticle

Abstract

Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95% CI = 1.2-1.9) and physical health (OR = 1.3, 95% CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95% CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.

Original languageEnglish
Pages (from-to)46-53
Number of pages8
JournalSchizophrenia Research
Volume201
DOIs
Publication statusPublished - Nov 2018

Fingerprint

Health Surveys
Mental Health
Quality of Life
Mental Disorders
Social Support
Logistic Models
Social Adjustment
Diagnostic Self Evaluation
Diagnostic and Statistical Manual of Mental Disorders
Health Status
Demography
Global Health
Health

Cite this

The association between psychotic experiences and health-related quality of life : a cross-national analysis based on World Mental Health Surveys. / WHO World Mental Health Survey Collaborators.

In: Schizophrenia Research, Vol. 201, 11.2018, p. 46-53.

Research output: Contribution to journalArticle

@article{8a4322b93fa8412e977c32fdb7b2072c,
title = "The association between psychotic experiences and health-related quality of life: a cross-national analysis based on World Mental Health Surveys",
abstract = "Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95{\%} CI = 1.2-1.9) and physical health (OR = 1.3, 95{\%} CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95{\%} CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.",
author = "{WHO World Mental Health Survey Collaborators} and Jordi Alonso and Sukanta Saha and Lim, {Carmen C W} and Sergio Aguilar-Gaxiola and Ali Al-Hamzawi and Corina Benjet and Bromet, {Evelyn J} and Louisa Degenhardt and {de Girolamo}, Giovanni and Oluyomi Esan and Silvia Florescu and Oye Gureje and Haro, {Josep M} and Chiyi Hu and Karam, {Elie G} and Georges Karam and Viviane Kovess-Masfety and Jean-Pierre Lepine and Sing Lee and Zeina Mneimneh and Fernando Navarro-Mateu and Jose Posada-Villa and Sampson, {Nancy A} and Scott, {Kate M} and Stagnaro, {Juan Carlos} and {Ten Have}, Margreet and Viana, {Maria Carmen} and Kessler, {Ronald C} and McGrath, {John J}",
note = "Copyright {\circledC} 2018 Elsevier B.V. All rights reserved.",
year = "2018",
month = "11",
doi = "10.1016/j.schres.2018.04.044",
language = "English",
volume = "201",
pages = "46--53",
journal = "Schizophrenia Research",
issn = "0920-9964",
publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - The association between psychotic experiences and health-related quality of life

T2 - a cross-national analysis based on World Mental Health Surveys

AU - WHO World Mental Health Survey Collaborators

AU - Alonso, Jordi

AU - Saha, Sukanta

AU - Lim, Carmen C W

AU - Aguilar-Gaxiola, Sergio

AU - Al-Hamzawi, Ali

AU - Benjet, Corina

AU - Bromet, Evelyn J

AU - Degenhardt, Louisa

AU - de Girolamo, Giovanni

AU - Esan, Oluyomi

AU - Florescu, Silvia

AU - Gureje, Oye

AU - Haro, Josep M

AU - Hu, Chiyi

AU - Karam, Elie G

AU - Karam, Georges

AU - Kovess-Masfety, Viviane

AU - Lepine, Jean-Pierre

AU - Lee, Sing

AU - Mneimneh, Zeina

AU - Navarro-Mateu, Fernando

AU - Posada-Villa, Jose

AU - Sampson, Nancy A

AU - Scott, Kate M

AU - Stagnaro, Juan Carlos

AU - Ten Have, Margreet

AU - Viana, Maria Carmen

AU - Kessler, Ronald C

AU - McGrath, John J

N1 - Copyright © 2018 Elsevier B.V. All rights reserved.

PY - 2018/11

Y1 - 2018/11

N2 - Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95% CI = 1.2-1.9) and physical health (OR = 1.3, 95% CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95% CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.

AB - Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95% CI = 1.2-1.9) and physical health (OR = 1.3, 95% CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95% CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.

U2 - 10.1016/j.schres.2018.04.044

DO - 10.1016/j.schres.2018.04.044

M3 - Article

C2 - 29778294

VL - 201

SP - 46

EP - 53

JO - Schizophrenia Research

JF - Schizophrenia Research

SN - 0920-9964

ER -