Abstract
Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95% CI = 1.2-1.9) and physical health (OR = 1.3, 95% CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95% CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.
| Original language | English |
|---|---|
| Pages (from-to) | 46-53 |
| Number of pages | 8 |
| Journal | Schizophrenia Research |
| Volume | 201 |
| DOIs | |
| Publication status | Published - Nov 2018 |
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The association between psychotic experiences and health-related quality of life : a cross-national analysis based on World Mental Health Surveys. / WHO World Mental Health Survey Collaborators.
In: Schizophrenia Research, Vol. 201, 11.2018, p. 46-53.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The association between psychotic experiences and health-related quality of life
T2 - a cross-national analysis based on World Mental Health Surveys
AU - WHO World Mental Health Survey Collaborators
AU - Alonso, Jordi
AU - Saha, Sukanta
AU - Lim, Carmen C W
AU - Aguilar-Gaxiola, Sergio
AU - Al-Hamzawi, Ali
AU - Benjet, Corina
AU - Bromet, Evelyn J
AU - Degenhardt, Louisa
AU - de Girolamo, Giovanni
AU - Esan, Oluyomi
AU - Florescu, Silvia
AU - Gureje, Oye
AU - Haro, Josep M
AU - Hu, Chiyi
AU - Karam, Elie G
AU - Karam, Georges
AU - Kovess-Masfety, Viviane
AU - Lepine, Jean-Pierre
AU - Lee, Sing
AU - Mneimneh, Zeina
AU - Navarro-Mateu, Fernando
AU - Posada-Villa, Jose
AU - Sampson, Nancy A
AU - Scott, Kate M
AU - Stagnaro, Juan Carlos
AU - Ten Have, Margreet
AU - Viana, Maria Carmen
AU - Kessler, Ronald C
AU - McGrath, John J
N1 - Copyright © 2018 Elsevier B.V. All rights reserved.
PY - 2018/11
Y1 - 2018/11
N2 - Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95% CI = 1.2-1.9) and physical health (OR = 1.3, 95% CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95% CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.
AB - Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95% CI = 1.2-1.9) and physical health (OR = 1.3, 95% CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95% CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.
U2 - 10.1016/j.schres.2018.04.044
DO - 10.1016/j.schres.2018.04.044
M3 - Article
C2 - 29778294
VL - 201
SP - 46
EP - 53
JO - Schizophrenia Research
JF - Schizophrenia Research
SN - 0920-9964
ER -