The association of use of sunbeds with cutaneous malignant melanoma and other skin cancers: A systematic review

Adele Green, Philippe Autier, Mathieu Boniol, Peter Boyle, Jean Francois Doré, Sara Gandini, Julia Newton-Bishop, Béatrice Secretan, Stephen J. Walter, Martin A. Weinstock, Johan Westerdahl

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Abstract

Exposure to solar ultraviolet (UV) radiation is a known cause of skin cancer. Sunbed use represents an increasingly frequent source of artificial UV exposure in light-skinned populations. To assess the available evidence of the association between sunbed use and cutaneous malignant melanoma (melanoma) and other skin cancers, a systematic review of the literature till March 2006 on epidemiological and biological studies on sunbed use was performed in Pubmed, ISI Web of Science, Embase, Pascal, Cochrane library, Lilacs and Medcarib. Search for keywords in the title and in the abstract was done systematically and supplemented by manual searches. Only case-control, cohort or cross-sectional studies were selected. Data were abstracted by means of a standardized data-collection protocol. Based on 19 informative studies, ever-use of sunbeds was positively associated with melanoma (summary relative risk, 1.15; 95% CI, 1.00-1.31), although there was no consistent evidence of a dose-response relationship. First exposure to sunbeds before 35 years of age significantly increased the risk of melanoma, based on 7 informative studies (summary relative risk, 1.75; 95% CI, 1.35-2.26). The summary relative risk of 3 studies of squamous cell carcinoma showed an increased risk. For basal cell carcinoma, the studies did not support an association. The evidence does not support a protective effect of the use of sunbeds against damage to the skin from subsequent sun exposure. Young adults should be discouraged from using indoor tanning equipment and restricted access to sunbeds by minors should be strongly considered.

Original languageEnglish
Pages (from-to)1116-1122
Number of pages7
JournalInternational Journal of Cancer
Volume120
Issue number5
DOIs
Publication statusPublished - Mar 1 2007

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Keywords

  • Artificial UV
  • Melanoma
  • Meta-analysis
  • Skin cancer
  • Sunbeds

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Green, A., Autier, P., Boniol, M., Boyle, P., Doré, J. F., Gandini, S., Newton-Bishop, J., Secretan, B., Walter, S. J., Weinstock, M. A., & Westerdahl, J. (2007). The association of use of sunbeds with cutaneous malignant melanoma and other skin cancers: A systematic review. International Journal of Cancer, 120(5), 1116-1122. https://doi.org/10.1002/ijc.22453