Sera collected from mice rejecting an allogeneic tumor and showing arming activity for normal splenocytes increased target cell lysis by immune cells when low (≤25:1) attacker:target cell ratios (A:T) were used but inhibited cytotoxicity at higher (100:1) A:T. The importance of this methodologic variable in studies of serum activity on cellular cytotoxicity is emphasized and the possible mechanisms are discussed.
|Number of pages||2|
|Journal||Journal of the National Cancer Institute|
|Publication status||Published - 1975|
ASJC Scopus subject areas
- Cancer Research