The auditory p300-based SSBCI: a door to minimally conscious patients?

G. R. Müller-Putz, D. S. Klobassa, C. Pokorny, G. Pichler, H. Erlbeck, R. G. Real, A. Kübler, M. Risetti, D. Mattia

Research output: Contribution to journalArticlepeer-review


In this study we report on the evaluation of a novel auditory single-switch BCI in nine patients diagnosed with MCS. The task included a simple and a complex oddball paradigm, the latter uses the tone stream segregation phenomenon. In all patients a significant difference between deviant and frequent tones could be observed in EEG. However, in some cases the deviant tones produce a significant negative peak and in some a very late positive peak. These preliminary findings are relevant in order to address future customization of this auditory ssBCI-based paradigm for unresponsive patients.

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics


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