The autonomic nervous system and cardiovascular disease

Role of n-3 PUFAs

Maria Teresa La Rovere, Jeppe Hagstrup Christensen

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In the last decades, a large body of experimental and clinical evidence has been accumulated showing that cardiovascular diseases are often accompanied by an imbalance in the sympathetic-vagal outflow to the heart, resulting in a chronic adrenergic activation. The arterial baroreceptor system is a key component of mechanisms contributing to the neural regulation of the cardiovascular system. Several methods have been proposed to assess autonomic activity by analyzing heart rate and blood pressure changes either spontaneously occurring or following provocations. The autonomic nervous system has been regarded as one of the putative mechanisms involved into the beneficial effects of exposure to n-3 fatty acids observed in epidemiological studies. The aim of the present review is to provide an update on the clinical evidence proposed so far linking exposure to n-3 fatty acids to autonomic nervous system modulation.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalVascular Pharmacology
Volume71
DOIs
Publication statusPublished - Aug 1 2015

Fingerprint

Autonomic Nervous System Diseases
Autonomic Nervous System
Omega-3 Fatty Acids
Cardiovascular Diseases
Pressoreceptors
Cardiovascular System
Adrenergic Agents
Epidemiologic Studies
Heart Rate
Blood Pressure

Keywords

  • Autonomic nervous system
  • Baroreflex sensitivity
  • Cardiovascular disease
  • Heart rate variability
  • N-3 PUFA

ASJC Scopus subject areas

  • Pharmacology
  • Molecular Medicine
  • Physiology

Cite this

The autonomic nervous system and cardiovascular disease : Role of n-3 PUFAs. / La Rovere, Maria Teresa; Christensen, Jeppe Hagstrup.

In: Vascular Pharmacology, Vol. 71, 01.08.2015, p. 1-10.

Research output: Contribution to journalArticle

@article{f159ae8d3ed541fb97caa434f8125898,
title = "The autonomic nervous system and cardiovascular disease: Role of n-3 PUFAs",
abstract = "In the last decades, a large body of experimental and clinical evidence has been accumulated showing that cardiovascular diseases are often accompanied by an imbalance in the sympathetic-vagal outflow to the heart, resulting in a chronic adrenergic activation. The arterial baroreceptor system is a key component of mechanisms contributing to the neural regulation of the cardiovascular system. Several methods have been proposed to assess autonomic activity by analyzing heart rate and blood pressure changes either spontaneously occurring or following provocations. The autonomic nervous system has been regarded as one of the putative mechanisms involved into the beneficial effects of exposure to n-3 fatty acids observed in epidemiological studies. The aim of the present review is to provide an update on the clinical evidence proposed so far linking exposure to n-3 fatty acids to autonomic nervous system modulation.",
keywords = "Autonomic nervous system, Baroreflex sensitivity, Cardiovascular disease, Heart rate variability, N-3 PUFA",
author = "{La Rovere}, {Maria Teresa} and Christensen, {Jeppe Hagstrup}",
year = "2015",
month = "8",
day = "1",
doi = "10.1016/j.vph.2015.02.005",
language = "English",
volume = "71",
pages = "1--10",
journal = "Vascular Pharmacology",
issn = "1537-1891",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - The autonomic nervous system and cardiovascular disease

T2 - Role of n-3 PUFAs

AU - La Rovere, Maria Teresa

AU - Christensen, Jeppe Hagstrup

PY - 2015/8/1

Y1 - 2015/8/1

N2 - In the last decades, a large body of experimental and clinical evidence has been accumulated showing that cardiovascular diseases are often accompanied by an imbalance in the sympathetic-vagal outflow to the heart, resulting in a chronic adrenergic activation. The arterial baroreceptor system is a key component of mechanisms contributing to the neural regulation of the cardiovascular system. Several methods have been proposed to assess autonomic activity by analyzing heart rate and blood pressure changes either spontaneously occurring or following provocations. The autonomic nervous system has been regarded as one of the putative mechanisms involved into the beneficial effects of exposure to n-3 fatty acids observed in epidemiological studies. The aim of the present review is to provide an update on the clinical evidence proposed so far linking exposure to n-3 fatty acids to autonomic nervous system modulation.

AB - In the last decades, a large body of experimental and clinical evidence has been accumulated showing that cardiovascular diseases are often accompanied by an imbalance in the sympathetic-vagal outflow to the heart, resulting in a chronic adrenergic activation. The arterial baroreceptor system is a key component of mechanisms contributing to the neural regulation of the cardiovascular system. Several methods have been proposed to assess autonomic activity by analyzing heart rate and blood pressure changes either spontaneously occurring or following provocations. The autonomic nervous system has been regarded as one of the putative mechanisms involved into the beneficial effects of exposure to n-3 fatty acids observed in epidemiological studies. The aim of the present review is to provide an update on the clinical evidence proposed so far linking exposure to n-3 fatty acids to autonomic nervous system modulation.

KW - Autonomic nervous system

KW - Baroreflex sensitivity

KW - Cardiovascular disease

KW - Heart rate variability

KW - N-3 PUFA

UR - http://www.scopus.com/inward/record.url?scp=84937966278&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84937966278&partnerID=8YFLogxK

U2 - 10.1016/j.vph.2015.02.005

DO - 10.1016/j.vph.2015.02.005

M3 - Article

VL - 71

SP - 1

EP - 10

JO - Vascular Pharmacology

JF - Vascular Pharmacology

SN - 1537-1891

ER -