The bereitschaftspotential preceding simple foot movement and initiation of gait in Parkinson's disease

M. Vidailhet, F. Stocchi, J. C. Rothwell, P. D. Thompson, B. L. Day, D. J. Brooks, C. D. Marsden

Research output: Contribution to journalArticle

Abstract

We compared the Bereitschaftspotential preceding a simple foot movement while sitting and a stepping movement while standing in a group of normal subjects and seven patients with mild to moderate Parkinson's disease (PD) while off medication. None had major difficulties stepping to initiate gait. Electromyographic signals from tibialis anterior triggered the averaging of electroencephalographic signals from the scalp. Bereitschaftspotentials preceding a standing stepping movement were larger than those before a foot movement while sitting in normal subjects, but no difference was observed in patients with PD. The absence of an increase in the Bereitschaftspotential when stepping in PD may reflect an impairment of the preparation and assembly of the complex sequences of movement necessary to initiate walking, even in the early stages of the illness.

Original languageEnglish
Pages (from-to)1784-1788
Number of pages5
JournalNeurology
Volume43
Issue number9
Publication statusPublished - Sep 1993

ASJC Scopus subject areas

  • Neuroscience(all)

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    Vidailhet, M., Stocchi, F., Rothwell, J. C., Thompson, P. D., Day, B. L., Brooks, D. J., & Marsden, C. D. (1993). The bereitschaftspotential preceding simple foot movement and initiation of gait in Parkinson's disease. Neurology, 43(9), 1784-1788.