Abstract
The bone marrow karyotype was studied in 17 patients affected by refractory anemia with excess of blasts (RAEB). A cytogenetic finding common to nearly all the cases is hypodiploidy, present in even quite high percentages. In 3 patients were identified the same interstitial deletion of the long arm of a chromosome 5, present in a percentage varying between 30% and 65%. The presence of this chromosomal anomaly appears to correspond to a slower development of the illness and transformation into acute leukemia seems rare or delayed.
| Original language | English |
|---|---|
| Pages (from-to) | 220-224 |
| Number of pages | 5 |
| Journal | Annales de Genetique |
| Volume | 26 |
| Issue number | 4 |
| Publication status | Published - 1983 |
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ASJC Scopus subject areas
- Genetics
Cite this
Lavezzi, A. M., Maiolo, A. T., Chiorboli, O., & Mozzana, R. (1983). The bone marrow karyotype in seventeen cases of refractory anemia with excess of blasts (RAEB). Annales de Genetique, 26(4), 220-224.