The bone marrow karyotype in seventeen cases of refractory anemia with excess of blasts (RAEB)

A. M. Lavezzi, A. T. Maiolo, O. Chiorboli, R. Mozzana

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Abstract

The bone marrow karyotype was studied in 17 patients affected by refractory anemia with excess of blasts (RAEB). A cytogenetic finding common to nearly all the cases is hypodiploidy, present in even quite high percentages. In 3 patients were identified the same interstitial deletion of the long arm of a chromosome 5, present in a percentage varying between 30% and 65%. The presence of this chromosomal anomaly appears to correspond to a slower development of the illness and transformation into acute leukemia seems rare or delayed.

Original languageEnglish
Pages (from-to)220-224
Number of pages5
JournalAnnales de Genetique
Volume26
Issue number4
Publication statusPublished - 1983

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ASJC Scopus subject areas

  • Genetics

Cite this

Lavezzi, A. M., Maiolo, A. T., Chiorboli, O., & Mozzana, R. (1983). The bone marrow karyotype in seventeen cases of refractory anemia with excess of blasts (RAEB). Annales de Genetique, 26(4), 220-224.