The cadaver kidney transplantation programme of milano: Immunologicall report

Girolamo Sirchia, Francesco Mercuriali, Mario Scalamogna, Vittorio Rosso di San Secondo, Claudia Pizzi, Francesca Poli

Research output: Contribution to journalArticle

Abstract

A retrospective investigation was carried out to evaluate the influence of HLA (A, B) matching, blood transfusions, and preexistence of lymphocytotoxic antibodies on the outcome of the cadaver kidney graft: Only non-NIH standard antibodies were considered, since patients with NIH standard antibodies do not undergo transplantation in the programme of Milano. It was found that (1) about one-half the patients with transplants had antibodies in their pretransplant serum. The preexistence of antibodies directed against B lymphocytes had an unfavourable effect on the graft survival; (2) the graft did particularly well in the nonimmunized patients who had been previously transfused; the graft survival was about 80% at 3 years in these patients; and (3) the HLA (A, B) match influenced the graft survival only in patients with antibodies.

Original languageEnglish
Pages (from-to)391-395
Number of pages5
JournalTransplantation
Volume23
Issue number5
Publication statusPublished - 1977

Fingerprint

Cadaver
Kidney Transplantation
Graft Survival
Antibodies
HLA-A Antigens
HLA-B Antigens
Transplants
Antilymphocyte Serum
Blood Transfusion
B-Lymphocytes
Transplantation
Kidney
Serum

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Sirchia, G., Mercuriali, F., Scalamogna, M., di San Secondo, V. R., Pizzi, C., & Poli, F. (1977). The cadaver kidney transplantation programme of milano: Immunologicall report. Transplantation, 23(5), 391-395.

The cadaver kidney transplantation programme of milano : Immunologicall report. / Sirchia, Girolamo; Mercuriali, Francesco; Scalamogna, Mario; di San Secondo, Vittorio Rosso; Pizzi, Claudia; Poli, Francesca.

In: Transplantation, Vol. 23, No. 5, 1977, p. 391-395.

Research output: Contribution to journalArticle

Sirchia, G, Mercuriali, F, Scalamogna, M, di San Secondo, VR, Pizzi, C & Poli, F 1977, 'The cadaver kidney transplantation programme of milano: Immunologicall report', Transplantation, vol. 23, no. 5, pp. 391-395.
Sirchia G, Mercuriali F, Scalamogna M, di San Secondo VR, Pizzi C, Poli F. The cadaver kidney transplantation programme of milano: Immunologicall report. Transplantation. 1977;23(5):391-395.
Sirchia, Girolamo ; Mercuriali, Francesco ; Scalamogna, Mario ; di San Secondo, Vittorio Rosso ; Pizzi, Claudia ; Poli, Francesca. / The cadaver kidney transplantation programme of milano : Immunologicall report. In: Transplantation. 1977 ; Vol. 23, No. 5. pp. 391-395.
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