The Caregiver Burden Inventory in evaluating the burden of caregivers of elderly demented patients: Results from a multicenter study

Martina Marvardi, Paola Mattioli, Liana Spazzafumo, Roberta Mastriforti, Patrizia Rinaldi, Maria Cristina Polidori, Antonio Cherubini, Roberto Quartesan, Luisa Bartorelli, Salvatore Bonaiuto, Domenico Cucinotta, Angelo Di Iorio, Maurizio Gallucci, Marcello Giordano, Marina Martorelli, Giorgio Masaraki, Antonio Nieddu, Carla Pettenati, Paolo Putzu, Vincenzo SolfrizziAldo Edoardo Tammaro, Pia Francesca Tomassini, Carlo Vergani, Umberto Senin, Patrizia Mecocci

Research output: Contribution to journalArticlepeer-review


Background and aims: The burden perceived by caregivers of patients with dementia is a fundamental prognostic aspect in the history of the disease. The aim of this study was to demonstrate the internal consistency of the Caregiver Burden Inventory (CBI), a scale used to quantify burdens in different aspects of a caregiver's life, and the influence of patients' and caregivers' characteristics on its different dimensions. Methods: In this cross-sectional study, 419 demented patients and their caregivers were evaluated in 16 geriatric centers in Italy. Cognitive status and behavioral disturbances were assessed by the Mini Mental State Examination (MMSE) and Neuropsychiatric Inventory (NPI), respectively. Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) were also evaluated. Comorbidity was assessed by the Cumulative Illness Rating Scale (CIRS). The severity of dementia was evaluated by the Clinical Dementia Rating (CDR) score. Caregiver distress due to the behavioral problems of the patient was assessed by the Neuropsychiatric Inventory-Distress, a subscale of the NPI wich evaluates stress caused by each behavioral disturbance of the patient, and by the Brief Symptom Inventory wich evaluates anxiety and depression. Burden was evaluated by the CBI. Results: The CBI showed very high internal consistency (Cronbach's alpha value >0.80). Factor analysis showed that the items clustered into four dimensions, and not five as originally proposed. Multiple regression analysis revealed that patients' behavioral disturbances and disability were the major predictors of the time-dependent burden; the psychophysical burden was explained mainly by caregiver anxiety and depression. Conclusions: The CBI proved to be an effective multidimensional tool for evaluating the impact of burden on many aspects of caregivers' lives.

Original languageEnglish
Pages (from-to)46-53
Number of pages8
JournalAging clinical and experimental research
Issue number1
Publication statusPublished - 2005


  • Burden
  • Caregiver
  • Dementia
  • Evaluation

ASJC Scopus subject areas

  • Ageing


Dive into the research topics of 'The Caregiver Burden Inventory in evaluating the burden of caregivers of elderly demented patients: Results from a multicenter study'. Together they form a unique fingerprint.

Cite this