The cerebellum contributes to higher functions during development. Evidence from a series of children surgically treated for posterior fossa tumours

Daria Riva, Cesare Giorgi

Research output: Contribution to journalArticle

489 Citations (Scopus)

Abstract

We present data on the intellectual, language and executive functions of 26 children who had undergone surgery for the removal of cerebellar hemisphere or vermal tumours. The children with right cerebellar tumours presented with disturbances of auditory sequential memory and language processing, whereas those with left cerebellar tumours showed deficits on tests of spatial and visual sequential memory. The vermal lesions led to two profiles: (i) post-surgical mutism, which evolved into speech disorders or language disturbances similar to agrammatism; and (ii) behavioural disturbances ranging from irritability to behaviours reminiscent of autism. These data are consistent with the recently acknowledged role of the cerebellum as a modulator of mental and social functions, and suggest that this role is operative early in childhood.

Original languageEnglish
Pages (from-to)1051-1061
Number of pages11
JournalBrain
Volume123
Issue number5
Publication statusPublished - May 2000

Fingerprint

Infratentorial Neoplasms
Cerebellar Neoplasms
Cerebellum
Language
Mutism
Broca Aphasia
Speech Disorders
Executive Function
Autistic Disorder
Neoplasms

Keywords

  • Cerebellum
  • Children
  • Frontal functions
  • Intelligence
  • Language
  • Social behaviour

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The cerebellum contributes to higher functions during development. Evidence from a series of children surgically treated for posterior fossa tumours. / Riva, Daria; Giorgi, Cesare.

In: Brain, Vol. 123, No. 5, 05.2000, p. 1051-1061.

Research output: Contribution to journalArticle

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