The changing HIV epidemic in Italian pregnant women

S. Fiore, A. E. Semprini, M. Ravizza, A. Bucceri, M. L. Muggiasca, B. Guerra, A. Spinillo, G. Pardi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: To describe changes in the characteristics of HIV-pregnant women in Italy and the impact of strategies for prevention of HIV vertical transmission. Study design: Since 1985, HIV-infected women and their children are followed in 23 European centres in the European Collaborative Study (ECS), according to a standard protocol. Eight Italian Obstetric units participating in the ECS enrolled 815 patients. Results: Overall use of zidovudine to reduce HIV vertical transmission has increased significantly since 1994 and between 1995 and 1997, 57% of Italian women were treated. However, 27% of babies received the infant component of the 076 regimen. Over the years, age at delivery has increased and their CD4 count at delivery decreased, most likely reflecting heterosexually infected women with a longer duration of infection. The increasing rate of elective caesarean section (42%) is not related to maternal, foetal or obstetrical indications, but its use as an intervention to reduce HIV vertical transmission. Conclusions: The identification of HIV-infected women during pregnancy or before delivery ensures the appropriate management of the woman and her child, and clinicians should be aware of the increasing number of women with heterosexual acquisition of HIV-infection who may be less easily identified. (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)149-153
Number of pages5
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume91
Issue number2
DOIs
Publication statusPublished - Aug 2000

Fingerprint

Pregnant Women
HIV
Zidovudine
Heterosexuality
CD4 Lymphocyte Count
Cesarean Section
Italy
Obstetrics
HIV Infections
Mothers
Pregnancy
Infection

Keywords

  • HIV
  • Italy
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Fiore, S., Semprini, A. E., Ravizza, M., Bucceri, A., Muggiasca, M. L., Guerra, B., ... Pardi, G. (2000). The changing HIV epidemic in Italian pregnant women. European Journal of Obstetrics and Gynecology and Reproductive Biology, 91(2), 149-153. https://doi.org/10.1016/S0301-2115(99)00268-7

The changing HIV epidemic in Italian pregnant women. / Fiore, S.; Semprini, A. E.; Ravizza, M.; Bucceri, A.; Muggiasca, M. L.; Guerra, B.; Spinillo, A.; Pardi, G.

In: European Journal of Obstetrics and Gynecology and Reproductive Biology, Vol. 91, No. 2, 08.2000, p. 149-153.

Research output: Contribution to journalArticle

Fiore, S, Semprini, AE, Ravizza, M, Bucceri, A, Muggiasca, ML, Guerra, B, Spinillo, A & Pardi, G 2000, 'The changing HIV epidemic in Italian pregnant women', European Journal of Obstetrics and Gynecology and Reproductive Biology, vol. 91, no. 2, pp. 149-153. https://doi.org/10.1016/S0301-2115(99)00268-7
Fiore, S. ; Semprini, A. E. ; Ravizza, M. ; Bucceri, A. ; Muggiasca, M. L. ; Guerra, B. ; Spinillo, A. ; Pardi, G. / The changing HIV epidemic in Italian pregnant women. In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 2000 ; Vol. 91, No. 2. pp. 149-153.
@article{539136b5f3494a7d864d906f96d2a3a8,
title = "The changing HIV epidemic in Italian pregnant women",
abstract = "Objective: To describe changes in the characteristics of HIV-pregnant women in Italy and the impact of strategies for prevention of HIV vertical transmission. Study design: Since 1985, HIV-infected women and their children are followed in 23 European centres in the European Collaborative Study (ECS), according to a standard protocol. Eight Italian Obstetric units participating in the ECS enrolled 815 patients. Results: Overall use of zidovudine to reduce HIV vertical transmission has increased significantly since 1994 and between 1995 and 1997, 57{\%} of Italian women were treated. However, 27{\%} of babies received the infant component of the 076 regimen. Over the years, age at delivery has increased and their CD4 count at delivery decreased, most likely reflecting heterosexually infected women with a longer duration of infection. The increasing rate of elective caesarean section (42{\%}) is not related to maternal, foetal or obstetrical indications, but its use as an intervention to reduce HIV vertical transmission. Conclusions: The identification of HIV-infected women during pregnancy or before delivery ensures the appropriate management of the woman and her child, and clinicians should be aware of the increasing number of women with heterosexual acquisition of HIV-infection who may be less easily identified. (C) 2000 Elsevier Science Ireland Ltd.",
keywords = "HIV, Italy, Pregnancy",
author = "S. Fiore and Semprini, {A. E.} and M. Ravizza and A. Bucceri and Muggiasca, {M. L.} and B. Guerra and A. Spinillo and G. Pardi",
year = "2000",
month = "8",
doi = "10.1016/S0301-2115(99)00268-7",
language = "English",
volume = "91",
pages = "149--153",
journal = "European Journal of Obstetrics, Gynecology and Reproductive Biology",
issn = "0028-2243",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - The changing HIV epidemic in Italian pregnant women

AU - Fiore, S.

AU - Semprini, A. E.

AU - Ravizza, M.

AU - Bucceri, A.

AU - Muggiasca, M. L.

AU - Guerra, B.

AU - Spinillo, A.

AU - Pardi, G.

PY - 2000/8

Y1 - 2000/8

N2 - Objective: To describe changes in the characteristics of HIV-pregnant women in Italy and the impact of strategies for prevention of HIV vertical transmission. Study design: Since 1985, HIV-infected women and their children are followed in 23 European centres in the European Collaborative Study (ECS), according to a standard protocol. Eight Italian Obstetric units participating in the ECS enrolled 815 patients. Results: Overall use of zidovudine to reduce HIV vertical transmission has increased significantly since 1994 and between 1995 and 1997, 57% of Italian women were treated. However, 27% of babies received the infant component of the 076 regimen. Over the years, age at delivery has increased and their CD4 count at delivery decreased, most likely reflecting heterosexually infected women with a longer duration of infection. The increasing rate of elective caesarean section (42%) is not related to maternal, foetal or obstetrical indications, but its use as an intervention to reduce HIV vertical transmission. Conclusions: The identification of HIV-infected women during pregnancy or before delivery ensures the appropriate management of the woman and her child, and clinicians should be aware of the increasing number of women with heterosexual acquisition of HIV-infection who may be less easily identified. (C) 2000 Elsevier Science Ireland Ltd.

AB - Objective: To describe changes in the characteristics of HIV-pregnant women in Italy and the impact of strategies for prevention of HIV vertical transmission. Study design: Since 1985, HIV-infected women and their children are followed in 23 European centres in the European Collaborative Study (ECS), according to a standard protocol. Eight Italian Obstetric units participating in the ECS enrolled 815 patients. Results: Overall use of zidovudine to reduce HIV vertical transmission has increased significantly since 1994 and between 1995 and 1997, 57% of Italian women were treated. However, 27% of babies received the infant component of the 076 regimen. Over the years, age at delivery has increased and their CD4 count at delivery decreased, most likely reflecting heterosexually infected women with a longer duration of infection. The increasing rate of elective caesarean section (42%) is not related to maternal, foetal or obstetrical indications, but its use as an intervention to reduce HIV vertical transmission. Conclusions: The identification of HIV-infected women during pregnancy or before delivery ensures the appropriate management of the woman and her child, and clinicians should be aware of the increasing number of women with heterosexual acquisition of HIV-infection who may be less easily identified. (C) 2000 Elsevier Science Ireland Ltd.

KW - HIV

KW - Italy

KW - Pregnancy

UR - http://www.scopus.com/inward/record.url?scp=0034084729&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034084729&partnerID=8YFLogxK

U2 - 10.1016/S0301-2115(99)00268-7

DO - 10.1016/S0301-2115(99)00268-7

M3 - Article

VL - 91

SP - 149

EP - 153

JO - European Journal of Obstetrics, Gynecology and Reproductive Biology

JF - European Journal of Obstetrics, Gynecology and Reproductive Biology

SN - 0028-2243

IS - 2

ER -