EPIDEMIOLOGIA CLINICA DELLA NUTRIZIONE ARTIFICIALE (ECNA). RISULTATI DI UNO STUDIO PILOTA MULTICENTRICO

Translated title of the contribution: The clinical epidemiology of artificial nutrition: Results of a pilot multicentric study

M. Braga, P. F. Dionigi Bozzetti, D. Radrizzani, C. Salis, G. Scroccaro, S. Gelio, A. Messori, G. Tognoni, M. Zanello

Research output: Contribution to journalArticlepeer-review

Abstract

A network for the epidemiological surveillance of artificial nutrition (AN) and its adverse effects was developed and tested in 79 hospitals. AN was defined as calorie intake > 1000 kcal/day including both venous (PN) and enteral (EN) routes. Included in the study were 1657 patients who underwent AN during 5 index days chosen 'a priori' twice monthly. Of these, 951 (57.4%) patients were observed in surgical departments, 473 (28.5%) in intensive care units and 233 (14.1%) in internal medicine departments. For each patient personal and anthropometric data, characteristics and adverse reactions of AN were collected. PN was carried out in 1396 (84.2%) patients (50.3% central TPN, 10.8% peripheral TPN, 23.1% PN + EN). EN alone was performed in 261 (13.8%) patients (85.1% nasogastric tube, 14.9% surgical stomies). The average daily calorie intake was 35 kcal/kg for central TPN (71% CHO, 29% fat), 26 kcal/kg for peripheral TPN and 33 kcal/kg for EN. Calorie intake exceeded BEE by 22% on average. The mean daily nitrogen intake was 0.19 g/kg for central TPN, 0.17 g/kg for peripheral TPN and 0.20 g/kg for EN. Adverse reactions were observed in 10.9% of PN patients (4.8% metabolic complications, 3.8% infections) and in 11.5% of EN patients (6.9% diarrhoea or disordered peristalsis). Adverse reactions were responsible for discontinuation of AN in 2.2% of parenterally supported patients and in 5.7% of enterally fed patients. The AN adverse reaction rate seems to be related to the severity of the clinical condition of patients.

Translated title of the contributionThe clinical epidemiology of artificial nutrition: Results of a pilot multicentric study
Original languageItalian
Pages (from-to)102-111
Number of pages10
JournalRivista Italiana di Nutrizione Parenterale ed Enterale
Volume10
Issue number2
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Food Science
  • Anatomy
  • Critical Care and Intensive Care Medicine
  • Nutrition and Dietetics

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