The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Mental retardation (MR), also known as intellectual dis- ability, is one of the most common neuropsychiatric dis- orders in infants, children and adolescents. Its prevalence in the general population is usually reported in the 1-3% range. Understanding its cause gives important benefits to the patient, his/her family, and the general practitio- ner. There is a diagnostic triad made up of intellectual functioning significantly below the mean, concurrent deficiencies in at least 2 areas of adaptive functioning, and onset before 18 years. This paves the way for MR to be scaled in different degrees and allows the distinction between intellectual and adaptive performance, and between adaptive and maladaptive behaviour. The sug- gested clinical approach comprises 6 main steps: 1) Fam- ily history, 2) personal history, 3) physical examination, clinical diagnosis, 5) imaging and laboratory diagnos- tics, 6) diagnostic synthesis and follow-up. New technol- ogies, such as array comparative genomic hybridisation (aCGH), are currently making a huge impact, shifting in many instances from a phenotype-first to a genotype-first approach. This emphasizes the need for a close collabora- tion between clinicians and laboratory professionals. The aim of clinical evaluation is to provide the best care for the patient, which relies on habilitation and counselling for his/her family.

Original languageEnglish
Title of host publicationGenetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability
PublisherS. Karger AG
Pages57-66
Number of pages10
Volume18
ISBN (Print)9783805592819, 9783805592802
DOIs
Publication statusPublished - Feb 15 2010

Fingerprint

Intellectual Disability
Aptitude
Comparative Genomic Hybridization
Psychological Adaptation
Diagnostic Imaging
General Practitioners
Physical Examination
Counseling
Patient Care
Rehabilitation
History
Genotype
Technology
Phenotype
Imaging techniques
Population

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Romano, C. (2010). The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability. In Genetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability (Vol. 18, pp. 57-66). S. Karger AG. https://doi.org/10.1002/9783805592819.ch5

The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability. / Romano, Corrado.

Genetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability. Vol. 18 S. Karger AG, 2010. p. 57-66.

Research output: Chapter in Book/Report/Conference proceedingChapter

Romano, C 2010, The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability. in Genetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability. vol. 18, S. Karger AG, pp. 57-66. https://doi.org/10.1002/9783805592819.ch5
Romano C. The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability. In Genetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability. Vol. 18. S. Karger AG. 2010. p. 57-66 https://doi.org/10.1002/9783805592819.ch5
Romano, Corrado. / The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability. Genetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability. Vol. 18 S. Karger AG, 2010. pp. 57-66
@inbook{28594263c841415e8867083d5b6cd981,
title = "The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability",
abstract = "Mental retardation (MR), also known as intellectual dis- ability, is one of the most common neuropsychiatric dis- orders in infants, children and adolescents. Its prevalence in the general population is usually reported in the 1-3{\%} range. Understanding its cause gives important benefits to the patient, his/her family, and the general practitio- ner. There is a diagnostic triad made up of intellectual functioning significantly below the mean, concurrent deficiencies in at least 2 areas of adaptive functioning, and onset before 18 years. This paves the way for MR to be scaled in different degrees and allows the distinction between intellectual and adaptive performance, and between adaptive and maladaptive behaviour. The sug- gested clinical approach comprises 6 main steps: 1) Fam- ily history, 2) personal history, 3) physical examination, clinical diagnosis, 5) imaging and laboratory diagnos- tics, 6) diagnostic synthesis and follow-up. New technol- ogies, such as array comparative genomic hybridisation (aCGH), are currently making a huge impact, shifting in many instances from a phenotype-first to a genotype-first approach. This emphasizes the need for a close collabora- tion between clinicians and laboratory professionals. The aim of clinical evaluation is to provide the best care for the patient, which relies on habilitation and counselling for his/her family.",
author = "Corrado Romano",
year = "2010",
month = "2",
day = "15",
doi = "10.1002/9783805592819.ch5",
language = "English",
isbn = "9783805592819",
volume = "18",
pages = "57--66",
booktitle = "Genetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability",
publisher = "S. Karger AG",

}

TY - CHAP

T1 - The Clinical Evaluation of Patients with Mental Retardation/Intellectual Disability

AU - Romano, Corrado

PY - 2010/2/15

Y1 - 2010/2/15

N2 - Mental retardation (MR), also known as intellectual dis- ability, is one of the most common neuropsychiatric dis- orders in infants, children and adolescents. Its prevalence in the general population is usually reported in the 1-3% range. Understanding its cause gives important benefits to the patient, his/her family, and the general practitio- ner. There is a diagnostic triad made up of intellectual functioning significantly below the mean, concurrent deficiencies in at least 2 areas of adaptive functioning, and onset before 18 years. This paves the way for MR to be scaled in different degrees and allows the distinction between intellectual and adaptive performance, and between adaptive and maladaptive behaviour. The sug- gested clinical approach comprises 6 main steps: 1) Fam- ily history, 2) personal history, 3) physical examination, clinical diagnosis, 5) imaging and laboratory diagnos- tics, 6) diagnostic synthesis and follow-up. New technol- ogies, such as array comparative genomic hybridisation (aCGH), are currently making a huge impact, shifting in many instances from a phenotype-first to a genotype-first approach. This emphasizes the need for a close collabora- tion between clinicians and laboratory professionals. The aim of clinical evaluation is to provide the best care for the patient, which relies on habilitation and counselling for his/her family.

AB - Mental retardation (MR), also known as intellectual dis- ability, is one of the most common neuropsychiatric dis- orders in infants, children and adolescents. Its prevalence in the general population is usually reported in the 1-3% range. Understanding its cause gives important benefits to the patient, his/her family, and the general practitio- ner. There is a diagnostic triad made up of intellectual functioning significantly below the mean, concurrent deficiencies in at least 2 areas of adaptive functioning, and onset before 18 years. This paves the way for MR to be scaled in different degrees and allows the distinction between intellectual and adaptive performance, and between adaptive and maladaptive behaviour. The sug- gested clinical approach comprises 6 main steps: 1) Fam- ily history, 2) personal history, 3) physical examination, clinical diagnosis, 5) imaging and laboratory diagnos- tics, 6) diagnostic synthesis and follow-up. New technol- ogies, such as array comparative genomic hybridisation (aCGH), are currently making a huge impact, shifting in many instances from a phenotype-first to a genotype-first approach. This emphasizes the need for a close collabora- tion between clinicians and laboratory professionals. The aim of clinical evaluation is to provide the best care for the patient, which relies on habilitation and counselling for his/her family.

UR - http://www.scopus.com/inward/record.url?scp=84872494396&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872494396&partnerID=8YFLogxK

U2 - 10.1002/9783805592819.ch5

DO - 10.1002/9783805592819.ch5

M3 - Chapter

AN - SCOPUS:84872494396

SN - 9783805592819

SN - 9783805592802

VL - 18

SP - 57

EP - 66

BT - Genetics of Mental Retardation: An Overview Encompassing Learning Disability and Intellectual Disability

PB - S. Karger AG

ER -