Abstract
Diabetic foot is a severe complication of diabetes mellitus that may affect up to 25% of patients in the course of their lifetime, with far-reaching effects on their quality of life, incidence of hospitalization, loss of independence, and even survival. It results from the interaction of the chronic micro- and macroangiopathic complications of diabetes, with a substantial role of neuropathy. This article reviews the pathophysiological mechanisms triggering these complications, how they interact and eventually lead to diabetic foot, and the therapeutic prospects - starting from prevention.
| Translated title of the contribution | The clinical pathophysiology of diabetic foot |
|---|---|
| Original language | Italian |
| Pages (from-to) | 22-31 |
| Number of pages | 10 |
| Journal | Giornale Italiano di Diabetologia e Metabolismo |
| Volume | 34 |
| Issue number | 1 |
| Publication status | Published - 2014 |
ASJC Scopus subject areas
- Endocrinology
- Internal Medicine
- Endocrinology, Diabetes and Metabolism