Abstract
Despite a huge number of studies, many aspects of the lipid transfer protein (LTP) syndrome, the most frequent primary food allergy in Mediterranean countries, remain unclear. Its peculiar geographical distribution, along with the extreme variability of its clinical expression, makes this type of food allergy something unique in the panorama of IgE-mediated food-induced allergic reactions. This review article tried to summarize the current knowledge about the most important aspects of LTP sensitization and allergy, along with the importance of positive and negative co-factors in the clinical expression of the syndrome as well as the issues regarding the cross-reactivity between LTPs present in botanically related and unrelated foods. Further, the possible absence of the protein from some plant foods is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 6-12 |
| Journal | Clinical and Experimental Allergy |
| Volume | 48 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2018 |
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Keywords
- Anaphylaxis
- Food allergy
- Lipid transfer protein
- Oral allergy syndrome
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
Cite this
The clinical relevance of lipid transfer protein. / Asero, R.; Piantanida, M.; Pinter, E.; Pravettoni, V.
In: Clinical and Experimental Allergy, Vol. 48, No. 1, 2018, p. 6-12.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The clinical relevance of lipid transfer protein
AU - Asero, R.
AU - Piantanida, M.
AU - Pinter, E.
AU - Pravettoni, V.
PY - 2018
Y1 - 2018
N2 - Despite a huge number of studies, many aspects of the lipid transfer protein (LTP) syndrome, the most frequent primary food allergy in Mediterranean countries, remain unclear. Its peculiar geographical distribution, along with the extreme variability of its clinical expression, makes this type of food allergy something unique in the panorama of IgE-mediated food-induced allergic reactions. This review article tried to summarize the current knowledge about the most important aspects of LTP sensitization and allergy, along with the importance of positive and negative co-factors in the clinical expression of the syndrome as well as the issues regarding the cross-reactivity between LTPs present in botanically related and unrelated foods. Further, the possible absence of the protein from some plant foods is discussed.
AB - Despite a huge number of studies, many aspects of the lipid transfer protein (LTP) syndrome, the most frequent primary food allergy in Mediterranean countries, remain unclear. Its peculiar geographical distribution, along with the extreme variability of its clinical expression, makes this type of food allergy something unique in the panorama of IgE-mediated food-induced allergic reactions. This review article tried to summarize the current knowledge about the most important aspects of LTP sensitization and allergy, along with the importance of positive and negative co-factors in the clinical expression of the syndrome as well as the issues regarding the cross-reactivity between LTPs present in botanically related and unrelated foods. Further, the possible absence of the protein from some plant foods is discussed.
KW - Anaphylaxis
KW - Food allergy
KW - Lipid transfer protein
KW - Oral allergy syndrome
UR - http://www.scopus.com/inward/record.url?scp=85036557486&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85036557486&partnerID=8YFLogxK
U2 - 10.1111/cea.13053
DO - 10.1111/cea.13053
M3 - Article
AN - SCOPUS:85036557486
VL - 48
SP - 6
EP - 12
JO - Clinical and Experimental Allergy
JF - Clinical and Experimental Allergy
SN - 0954-7894
IS - 1
ER -