The continuing challenge of gastrointestinal fistulae

M. Falconi, P. Pederzoli

Research output: Contribution to journalArticlepeer-review


The majority (75-85%) of gastrointestinal (GI) fistulae occur as complications after surgery, particularly following pancreaticoduodenectomy for malignant disease. Gastrointestinal fistulae are associated with a high morbidity rate, and can lead to further complications, such as disturbed fluid and electrolyte balance, sepsis and even death. Postoperative fistula formation also lengthens the recovery period, which increases hospital costs. Although fistula treatment has improved over time, the number of patients suffering from GI fistulae has not declined. This may be because, with improved surgical techniques and patient care, more complex surgery is being performed on patients with more advanced or complicated disease who are generally at higher risk. Therefore, the effective treatment and/or prevention of GI fistulae remain important issues in GI surgery.

Original languageEnglish
Pages (from-to)9-19
Number of pages11
JournalResearch and Clinical Forums
Issue number1
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Medicine(all)


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