The control of T cell responses by dendritic cell subsets

Steven D. Reid, Giuseppe Penna, Luciano Adorini

Research output: Contribution to journalArticlepeer-review

Abstract

Dendritic cells are known as the most efficient antigen-presenting cell type to activate naive T cells; however, they are able to do more than just efficiently present antigen to T cells. They are key modulators of the immune response that can influence Th cell differentiation by preferentially inducing Th type 1 or 2 cell responses, and the differential polarisation of CD4 + T cells appears to be mediated by discrete dendritic cell subsets.

Original languageEnglish
Pages (from-to)114-121
Number of pages8
JournalCurrent Opinion in Immunology
Volume12
Issue number1
DOIs
Publication statusPublished - Feb 1 2000

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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