The cortical somatotopic map and phantom phenomena in subjects with congenital limb atrophy and traumatic amputees with phantom limb pain

Pedro Montoya, Karin Ritter, Ellena Huse, Wolfgang Larbig, Christoph Braun, Stephanie Töpfner, Werner Lutzenberger, Wolfgang Grodd, Herta Flor, Niels Birbaumer

Research output: Contribution to journalArticle

Abstract

The extent of the cortical somatotopic map and its relationship to phantom phenomena was tested in five subjects with congenital absence of an upper limb, four traumatic amputees with phantom limb pain and five healthy controls. Cortical maps of the first and fifth digit of the intact hand, the lower lip and the first toe (bilaterally) were obtained using neuroelectric source imaging. The subjects with congenital upper limb atrophy showed symmetric positions of the left and right side of the lower lip and the first toe, whereas the traumatic amputees with pain showed a significant shift (about 2.4 cm) of the cortical representation of the lower lip towards the hand region contralateral to the amputation side but no shift for the toe representation. In healthy controls, no significant hemispheric differences between the cortical representation of the digits, lower lip or first toe were found. Phantom phenomena were absent in the congenital but extensive in the traumatic amputees. These data confirm the assumption that congenital absence of a limb does not lead to cortical reorganization or phantom limbs whereas traumatic amputations that are accompanied by phantom limb pain show shifts of the cortical areas adjacent to the amputation zone towards the representation of the deafferented body part.

Original languageEnglish
Pages (from-to)1095-1102
Number of pages8
JournalEuropean Journal of Neuroscience
Volume10
Issue number3
DOIs
Publication statusPublished - Mar 1998

Fingerprint

Phantom Limb
Amputees
Toes
Lip
Atrophy
Extremities
Amputation
Upper Extremity
Hand
Traumatic Amputation
Human Body
Pain

Keywords

  • Congenital aplasia
  • Cortical plasticity
  • Cortical reorganization
  • Phantom pain
  • Somatosensory cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The cortical somatotopic map and phantom phenomena in subjects with congenital limb atrophy and traumatic amputees with phantom limb pain. / Montoya, Pedro; Ritter, Karin; Huse, Ellena; Larbig, Wolfgang; Braun, Christoph; Töpfner, Stephanie; Lutzenberger, Werner; Grodd, Wolfgang; Flor, Herta; Birbaumer, Niels.

In: European Journal of Neuroscience, Vol. 10, No. 3, 03.1998, p. 1095-1102.

Research output: Contribution to journalArticle

Montoya, P, Ritter, K, Huse, E, Larbig, W, Braun, C, Töpfner, S, Lutzenberger, W, Grodd, W, Flor, H & Birbaumer, N 1998, 'The cortical somatotopic map and phantom phenomena in subjects with congenital limb atrophy and traumatic amputees with phantom limb pain', European Journal of Neuroscience, vol. 10, no. 3, pp. 1095-1102. https://doi.org/10.1046/j.1460-9568.1998.00122.x
Montoya, Pedro ; Ritter, Karin ; Huse, Ellena ; Larbig, Wolfgang ; Braun, Christoph ; Töpfner, Stephanie ; Lutzenberger, Werner ; Grodd, Wolfgang ; Flor, Herta ; Birbaumer, Niels. / The cortical somatotopic map and phantom phenomena in subjects with congenital limb atrophy and traumatic amputees with phantom limb pain. In: European Journal of Neuroscience. 1998 ; Vol. 10, No. 3. pp. 1095-1102.
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