ANDAMENTO DELL'EPILESSIA DURANTE LA GRAVIDANZA: STUDIO PROSPETTICO DI 164 CASI

Translated title of the contribution: The course of epilepsy during pregnancy: A prospective study of 164 cases

L. Minotti, M. P. Canevini, R. Mai, C. Fumarola, F. Molteni, A. Cappello, D. Battino, G. Pardi, R. Canger

Research output: Contribution to journalArticlepeer-review

Abstract

We analyzed the effect of pregnancy on seizure frequency in women with epilepsy (E) followed prospectively. From 1988 to 1991 we followed 164 women with E, 140 of which were term-pregnancies (24 abortion): seizure frequency was unchanged in 68%, increased in 26% and improved in 6% of pregnancies. In pts with increased seizure frequency during pregnancy, the highest increase was in the first trimester (54%); serum AED's levels were in range in 46%, below the therapeutic concentration in 43%; concerning the type of E, there was an increased seizure frequency in 29% of the pts with partial E and 17.5% of the pts with generalized idiopatic E; no difference was found between partial symptomatic (30%) and partial criptogenic (28%) E in the increase of seizure frequency. In the group of the pts affected by generalized idiopatic E we found a different risk of increased seizure frequency as follow: 7% for the pts with childhood and juvenile absence E, 17% for those with E with GTC seizures on awakening and 37.5% for those with JME.

Translated title of the contributionThe course of epilepsy during pregnancy: A prospective study of 164 cases
Original languageItalian
Pages (from-to)237-239
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number79-80
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Clinical Neurology

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