TY - JOUR
T1 - The development of hyperventilation in patients with chronic heart failure and Cheyne-Stokes respiration
T2 - A possible role of chronic hypoxia
AU - Fanfulla, Francesco
AU - Mortara, Andrea
AU - Maestri, Roberto
AU - Pinna, Gian Domenico
AU - Bruschi, Claudio
AU - Cobelli, Franco
AU - Rampulla, Ciro
PY - 1998
Y1 - 1998
N2 - Aim: To analyze the relationship between daytime respiratory and cardiac function in patients with compensated chronic heart failure (CHF) with and without periodic breathing (PB) or Cheyne-Stokes respiration (CSR). Patients: We studied 132 patients (female, 13%; mean age, 53±8 years; body mass index, 25.9±3.5 kg/m2; left ventricular ejection fraction 2 were similar in the three groups of patients considered. In contrast, patients with PB or CSR had an increased minute ventilation and reduced PaCO2 values. Interestingly, patients with PB or CSR had lower values of arterial content of O2. and systemic oxygen transport (SOT) than patients with a normal breathing pattern (SOT, 394±9.8, 347±9.6, 438±11 mL of O2/min/m2, respectively; analysis of variance p2 with PCWP (r=0.26; p2 was significantly correlated with SOT, LECT, and CI (r=0.51; r =0.26; p2=0.4; p
AB - Aim: To analyze the relationship between daytime respiratory and cardiac function in patients with compensated chronic heart failure (CHF) with and without periodic breathing (PB) or Cheyne-Stokes respiration (CSR). Patients: We studied 132 patients (female, 13%; mean age, 53±8 years; body mass index, 25.9±3.5 kg/m2; left ventricular ejection fraction 2 were similar in the three groups of patients considered. In contrast, patients with PB or CSR had an increased minute ventilation and reduced PaCO2 values. Interestingly, patients with PB or CSR had lower values of arterial content of O2. and systemic oxygen transport (SOT) than patients with a normal breathing pattern (SOT, 394±9.8, 347±9.6, 438±11 mL of O2/min/m2, respectively; analysis of variance p2 with PCWP (r=0.26; p2 was significantly correlated with SOT, LECT, and CI (r=0.51; r =0.26; p2=0.4; p
KW - Cheyne-Stokes respiration
KW - Chronic heart failure
KW - Oxygen
KW - Pattern of breathing
KW - Respiratory function
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M3 - Article
C2 - 9792581
AN - SCOPUS:0031732155
VL - 114
SP - 1083
EP - 1090
JO - Chest
JF - Chest
SN - 0012-3692
IS - 4
ER -