Abstract
Development of the vascular system involves a complex sequence of inductive and differentiating signals leading to vasculogenesis and/or angiogenesis. Dissecting and exploring this process in its multifaceted morphological and molecular aspects has represented a basic contribution and a fascinating adventure in the history of biology. Vasculogenesis, that is de novo formation of vascular channels, initiates early during embryo development and prevails at the beginning of embryo patterning and organ formation. Angiogenesis, the process of shaping new vessels from preexisting blood vessels, mainly operates during postnatal life. In this historical introduction, we try to retrace the early steps of scientific speculation on vascular development and to recapitulate the principal paths leading to our present appreciation of blood vessel formation.
| Original language | English |
|---|---|
| Title of host publication | Vascular Morphogenesis: Methods and Protocols |
| Publisher | Springer New York |
| Pages | 1-14 |
| Number of pages | 14 |
| ISBN (Print) | 9781493914623, 9781493914616 |
| DOIs | |
| Publication status | Published - Dec 2 2014 |
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Keywords
- Angiogenesis
- Endothelium
- Vascular system
- Vasculogenesis
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
Cite this
The development of the vascular system : A historical overview. / Ribatti, Domenico; Nico, Beatrice; Crivellato, Enrico.
Vascular Morphogenesis: Methods and Protocols. Springer New York, 2014. p. 1-14.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - The development of the vascular system
T2 - A historical overview
AU - Ribatti, Domenico
AU - Nico, Beatrice
AU - Crivellato, Enrico
PY - 2014/12/2
Y1 - 2014/12/2
N2 - Development of the vascular system involves a complex sequence of inductive and differentiating signals leading to vasculogenesis and/or angiogenesis. Dissecting and exploring this process in its multifaceted morphological and molecular aspects has represented a basic contribution and a fascinating adventure in the history of biology. Vasculogenesis, that is de novo formation of vascular channels, initiates early during embryo development and prevails at the beginning of embryo patterning and organ formation. Angiogenesis, the process of shaping new vessels from preexisting blood vessels, mainly operates during postnatal life. In this historical introduction, we try to retrace the early steps of scientific speculation on vascular development and to recapitulate the principal paths leading to our present appreciation of blood vessel formation.
AB - Development of the vascular system involves a complex sequence of inductive and differentiating signals leading to vasculogenesis and/or angiogenesis. Dissecting and exploring this process in its multifaceted morphological and molecular aspects has represented a basic contribution and a fascinating adventure in the history of biology. Vasculogenesis, that is de novo formation of vascular channels, initiates early during embryo development and prevails at the beginning of embryo patterning and organ formation. Angiogenesis, the process of shaping new vessels from preexisting blood vessels, mainly operates during postnatal life. In this historical introduction, we try to retrace the early steps of scientific speculation on vascular development and to recapitulate the principal paths leading to our present appreciation of blood vessel formation.
KW - Angiogenesis
KW - Endothelium
KW - Vascular system
KW - Vasculogenesis
UR - http://www.scopus.com/inward/record.url?scp=84955415466&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955415466&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-1462-3_1
DO - 10.1007/978-1-4939-1462-3_1
M3 - Chapter
SN - 9781493914623
SN - 9781493914616
SP - 1
EP - 14
BT - Vascular Morphogenesis: Methods and Protocols
PB - Springer New York
ER -