The development of the vascular system: A historical overview

Domenico Ribatti; Beatrice Nico; Enrico Crivellato

doi:10.1007/978-1-4939-1462-3_1

The development of the vascular system: A historical overview

Domenico Ribatti, Beatrice Nico, Enrico Crivellato

IRCCS Giovanni Paolo II

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Development of the vascular system involves a complex sequence of inductive and differentiating signals leading to vasculogenesis and/or angiogenesis. Dissecting and exploring this process in its multifaceted morphological and molecular aspects has represented a basic contribution and a fascinating adventure in the history of biology. Vasculogenesis, that is de novo formation of vascular channels, initiates early during embryo development and prevails at the beginning of embryo patterning and organ formation. Angiogenesis, the process of shaping new vessels from preexisting blood vessels, mainly operates during postnatal life. In this historical introduction, we try to retrace the early steps of scientific speculation on vascular development and to recapitulate the principal paths leading to our present appreciation of blood vessel formation.

Original language	English
Title of host publication	Vascular Morphogenesis: Methods and Protocols
Publisher	Springer New York
Pages	1-14
Number of pages	14
ISBN (Print)	9781493914623, 9781493914616
DOIs	https://doi.org/10.1007/978-1-4939-1462-3_1
Publication status	Published - Dec 2 2014

Keywords

Angiogenesis
Endothelium
Vascular system
Vasculogenesis

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

Access to Document

10.1007/978-1-4939-1462-3_1

Cite this

@inbook{c24b2f9a59554e649257c89263442a67,

title = "The development of the vascular system: A historical overview",

abstract = "Development of the vascular system involves a complex sequence of inductive and differentiating signals leading to vasculogenesis and/or angiogenesis. Dissecting and exploring this process in its multifaceted morphological and molecular aspects has represented a basic contribution and a fascinating adventure in the history of biology. Vasculogenesis, that is de novo formation of vascular channels, initiates early during embryo development and prevails at the beginning of embryo patterning and organ formation. Angiogenesis, the process of shaping new vessels from preexisting blood vessels, mainly operates during postnatal life. In this historical introduction, we try to retrace the early steps of scientific speculation on vascular development and to recapitulate the principal paths leading to our present appreciation of blood vessel formation.",

keywords = "Angiogenesis, Endothelium, Vascular system, Vasculogenesis",

author = "Domenico Ribatti and Beatrice Nico and Enrico Crivellato",

year = "2014",

month = dec,

day = "2",

doi = "10.1007/978-1-4939-1462-3_1",

language = "English",

isbn = "9781493914623",

pages = "1--14",

booktitle = "Vascular Morphogenesis: Methods and Protocols",

publisher = "Springer New York",

}

TY - CHAP

T1 - The development of the vascular system

T2 - A historical overview

AU - Ribatti, Domenico

AU - Nico, Beatrice

AU - Crivellato, Enrico

PY - 2014/12/2

Y1 - 2014/12/2

N2 - Development of the vascular system involves a complex sequence of inductive and differentiating signals leading to vasculogenesis and/or angiogenesis. Dissecting and exploring this process in its multifaceted morphological and molecular aspects has represented a basic contribution and a fascinating adventure in the history of biology. Vasculogenesis, that is de novo formation of vascular channels, initiates early during embryo development and prevails at the beginning of embryo patterning and organ formation. Angiogenesis, the process of shaping new vessels from preexisting blood vessels, mainly operates during postnatal life. In this historical introduction, we try to retrace the early steps of scientific speculation on vascular development and to recapitulate the principal paths leading to our present appreciation of blood vessel formation.

AB - Development of the vascular system involves a complex sequence of inductive and differentiating signals leading to vasculogenesis and/or angiogenesis. Dissecting and exploring this process in its multifaceted morphological and molecular aspects has represented a basic contribution and a fascinating adventure in the history of biology. Vasculogenesis, that is de novo formation of vascular channels, initiates early during embryo development and prevails at the beginning of embryo patterning and organ formation. Angiogenesis, the process of shaping new vessels from preexisting blood vessels, mainly operates during postnatal life. In this historical introduction, we try to retrace the early steps of scientific speculation on vascular development and to recapitulate the principal paths leading to our present appreciation of blood vessel formation.

KW - Angiogenesis

KW - Endothelium

KW - Vascular system

KW - Vasculogenesis

UR - http://www.scopus.com/inward/record.url?scp=84955415466&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84955415466&partnerID=8YFLogxK

U2 - 10.1007/978-1-4939-1462-3_1

DO - 10.1007/978-1-4939-1462-3_1

M3 - Chapter

SN - 9781493914623

SN - 9781493914616

SP - 1

EP - 14

BT - Vascular Morphogenesis: Methods and Protocols

PB - Springer New York

ER -

The development of the vascular system: A historical overview

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this