The differential involvement of inferior parietal lobule in number comparison: A rTMS study

Marco Sandrini, Paolo M. Rossini, Carlo Miniussi

Research output: Contribution to journalArticle

Abstract

Number processing is known to involve several sites within the posterior regions of parietal cortex. Here, we investigated whether neural activity in the inferior parietal lobule (IPL) is essential for number processing, by observing the effects of interfering with its activity during the execution of a standard number comparison task. Subjects performance on the task was significantly slowed down when we delivered trains of repetitive transcranial magnetic stimuli (rTMS) to the posterior parietal scalp site overlying the left IPL, while rTMS did not affect the number comparison task if delivered to homologous, contralateral (right) IPL. In conclusion, the present findings add support to a growing body of evidence from neuropsychology and neuroimaging studies that the left inferior parietal lobule is an important component of the networks subserving the representation of quantity.

Original languageEnglish
Pages (from-to)1902-1909
Number of pages8
JournalNeuropsychologia
Volume42
Issue number14
DOIs
Publication statusPublished - 2004

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Keywords

  • Number processing
  • Parietal cortex
  • Repetitive transcranial magnetic stimulation
  • rTMS

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Neuropsychology and Physiological Psychology

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