The durability of pulmonary vein isolation using the visually guided laser balloon catheter: Multicenter results of pulmonary vein remapping studies

Srinivas R. Dukkipati, Petr Neuzil, Josef Kautzner, Jan Petru, Dan Wichterle, Jan Skoda, Robert Cihak, Petr Peichl, Antonio Dello Russo, Gemma Pelargonio, Claudio Tondo, Andrea Natale, Vivek Y. Reddy

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The visually guided laser ablation (VGLA) catheter is a compliant, variable-diameter balloon that delivers laser energy around the pulmonary vein (PV) ostium under real-time endoscopic visualization. While acute PV isolation has been shown to be feasible, limited data exist regarding the durability of isolation. Objective: We sought to determine the durability of PV isolation following ablation using the balloon-based VGLA catheter. Methods: The VGLA catheter was evaluated in patients with paroxysmal atrial fibrillation (3 sites, 10 operators). Following transseptal puncture, the VGLA catheter was advanced through a 12-F deflectable sheath and inflated at the target PV ostium. Under endoscopic guidance, the 30° aiming arc was maneuvered around the PV and laser energy was delivered to ablate tissue in a contiguous/overlapping manner. At ∼3 months, all patients returned for a PV remapping procedure. Results: In 56 patients, 202 of 206 PVs (98%) were acutely isolated. At 105 ± 44 (mean ± SD) days, 52 patients returned for PV remapping at which time 162 of 189 PVs (86%) remained isolated and 32 of 52 patients (62%) had all PVs still isolated. On comparing the operators performing

Original languageEnglish
Pages (from-to)919-925
Number of pages7
JournalHeart Rhythm
Volume9
Issue number6
DOIs
Publication statusPublished - Jun 2012

Keywords

  • Ablation
  • Atrial fibrillation
  • Endoscopic visualization
  • Laser
  • Paroxysmal
  • Pulmonary veins

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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