The dynamics of Polycomb complexes

Research output: Contribution to journalArticle

Abstract

Polycomb complexes are essential regulators of embryonic and adult stem cells, highly conserved from flies to mammals. Traditionally, their study was based on biochemical and genetic approaches. More recently, the development of novel technologies and the improvement and standardization of existing ones has allowed to address previously unexplored aspects of Polycomb biology, such as dynamics and regulation. In this chapter, relevant researchers in the field discuss novel technologies aimed at dissecting the dynamics of Polycomb complexes in normal and pathological conditions.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalMethods in Molecular Biology
Volume1480
DOIs
Publication statusPublished - 2016

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Keywords

  • Automated imaging analysis
  • Fluorescence resonance energy transfer
  • Polycomb body
  • Polycomb complexes
  • Subcellular fractionation

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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