The effect of biophysical stimulation on cartilage repair with osteochondral autograft

S. Setti, M. Fini, F. Benazzo, R. Cadossi

Research output: Contribution to journalArticlepeer-review


A study was conducted to evaluate the effects of PEMFs on osteochondral graft healing by favoring subchodral bone integration and by limiting inflammation and cartilage degeneration. Osteochondral grafts were performed in the right knee of 20 sheep. Animals were treated with PEMFs. Grafts were evaluated by microradiographic and histological analyses. It shows that osteochodral grafting is an effective technique used in articular cartilage resurfacing. PEMF exposure favored the healing of osteochodral grafts in sheep. The experiment demostrates that using a biophysical stimulus with adenosine-agonist action, it is possible to perform on an individual joint a chodroprotective biophysical anotomic treatment of cartilage and subchodral bone.

Original languageEnglish
Pages (from-to)241-242
Number of pages2
JournalMCB Molecular and Cellular Biomechanics
Issue number4
Publication statusPublished - Dec 2006

ASJC Scopus subject areas

  • Biophysics
  • Cell Biology
  • Molecular Biology
  • Molecular Medicine


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