The effect of cytochalasin B, colchicine and vinblastine on the adhesion of Trichomonas vaginalis to glass surfaces

P. Cappuccinelli, L. Varesio

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The attachment of Trichomonas vaginalis to glass surfaces was studied in the presence of cytochalasin B, colchicine and vinblastine. Marked inhibition of adhesion was noted with high concentrations of cytochalasin B. Colchicine and vinblastine were without effect. These findings suggest that Trichomonas vaginalis adhesion is at least partially mediated by the extension of cellular probes, due to the action of cytochalasin-sensitive microfilaments.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalInternational Journal for Parasitology
Volume5
Issue number1
DOIs
Publication statusPublished - 1975

Fingerprint

Trichomonas vaginalis
Cytochalasin B
Vinblastine
Colchicine
Glass
Cytochalasins
Actin Cytoskeleton

Keywords

  • cellular projections
  • colchicine
  • cytochalasin B
  • intracellular microfilaments
  • intracellular microtubules
  • substrate adhesion
  • Trichomonas vaginalis
  • vinblastine

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

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abstract = "The attachment of Trichomonas vaginalis to glass surfaces was studied in the presence of cytochalasin B, colchicine and vinblastine. Marked inhibition of adhesion was noted with high concentrations of cytochalasin B. Colchicine and vinblastine were without effect. These findings suggest that Trichomonas vaginalis adhesion is at least partially mediated by the extension of cellular probes, due to the action of cytochalasin-sensitive microfilaments.",
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T1 - The effect of cytochalasin B, colchicine and vinblastine on the adhesion of Trichomonas vaginalis to glass surfaces

AU - Cappuccinelli, P.

AU - Varesio, L.

PY - 1975

Y1 - 1975

N2 - The attachment of Trichomonas vaginalis to glass surfaces was studied in the presence of cytochalasin B, colchicine and vinblastine. Marked inhibition of adhesion was noted with high concentrations of cytochalasin B. Colchicine and vinblastine were without effect. These findings suggest that Trichomonas vaginalis adhesion is at least partially mediated by the extension of cellular probes, due to the action of cytochalasin-sensitive microfilaments.

AB - The attachment of Trichomonas vaginalis to glass surfaces was studied in the presence of cytochalasin B, colchicine and vinblastine. Marked inhibition of adhesion was noted with high concentrations of cytochalasin B. Colchicine and vinblastine were without effect. These findings suggest that Trichomonas vaginalis adhesion is at least partially mediated by the extension of cellular probes, due to the action of cytochalasin-sensitive microfilaments.

KW - cellular projections

KW - colchicine

KW - cytochalasin B

KW - intracellular microfilaments

KW - intracellular microtubules

KW - substrate adhesion

KW - Trichomonas vaginalis

KW - vinblastine

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