The effect of cytochalasin B, colchicine and vinblastine on the adhesion of Trichomonas vaginalis to glass surfaces

P. Cappuccinelli, L. Varesio

Research output: Contribution to journalArticle

Abstract

The attachment of Trichomonas vaginalis to glass surfaces was studied in the presence of cytochalasin B, colchicine and vinblastine. Marked inhibition of adhesion was noted with high concentrations of cytochalasin B. Colchicine and vinblastine were without effect. These findings suggest that Trichomonas vaginalis adhesion is at least partially mediated by the extension of cellular probes, due to the action of cytochalasin-sensitive microfilaments.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalInternational Journal for Parasitology
Volume5
Issue number1
DOIs
Publication statusPublished - 1975

Keywords

  • cellular projections
  • colchicine
  • cytochalasin B
  • intracellular microfilaments
  • intracellular microtubules
  • substrate adhesion
  • Trichomonas vaginalis
  • vinblastine

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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