The effect of high doses of reduced glutathione on hepatic clearances and fibrogenetic activity in patients with chronic alcoholic liver disease

E. Bardellini, P. Bindi, S. Borzone, S. Caglieris, F. Dagnino, R. Testa

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Reduced glutathione at a dosage of 2400 mg daily was administered for 15 days to 10 patients with chronic alcoholic liver disease. Patients abstained from alcohol for 1 month before treatment. Clinical and biochemical parameters were evaluated. Clearances of orally administered galactose and chenodeoxycholic acid were determined as markers of liver function and blood levels of prolyl-hydroxylase were used as an index of hepatic fibrogenetic activity. For ethical reasons a control group was not included in the study and the results were considered statistically significant at P

Original languageEnglish
Pages (from-to)116-122
Number of pages7
JournalAdvances in Therapy
Issue number2
Publication statusPublished - 1992


ASJC Scopus subject areas

  • Medicine(all)

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