The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

Franco Maggiolo; Diego Ripamonti; Carlo Torti; Claudio Arici; Andrea Antinori; Eugenia Quiros-Roldan; Lorenzo Minoli; Laura Sighinolfi; Paola Nasta; Fredy Suter

The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

Franco Maggiolo, Diego Ripamonti, Carlo Torti, Claudio Arici, Andrea Antinori, Eugenia Quiros-Roldan, Lorenzo Minoli, Laura Sighinolfi, Paola Nasta, Fredy Suter

Research output: Contribution to journal › Article › peer-review

Abstract

Background: One of the more vigorous debates in the field of highly active antiretroviral therapy (HAART) is how to start it and what the optimal drug sequence is. Methods: A retrospective cohort analysis was performed. The aim was to evaluate which variables could influence the virological response to second-line genotypic-based HAART in patients with virological documented first-line HAART failure. A positive response was defined as a confirmed HIV RNA level

Original language	English
Pages (from-to)	923-929
Number of pages	7
Journal	Antiviral Therapy
Volume	11
Issue number	7
Publication status	Published - 2006

ASJC Scopus subject areas

Pharmacology

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The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens. / Maggiolo, Franco; Ripamonti, Diego; Torti, Carlo; Arici, Claudio; Antinori, Andrea; Quiros-Roldan, Eugenia; Minoli, Lorenzo; Sighinolfi, Laura; Nasta, Paola; Suter, Fredy.

In: Antiviral Therapy, Vol. 11, No. 7, 2006, p. 923-929.

Research output: Contribution to journal › Article › peer-review

Maggiolo, Franco ; Ripamonti, Diego ; Torti, Carlo ; Arici, Claudio ; Antinori, Andrea ; Quiros-Roldan, Eugenia ; Minoli, Lorenzo ; Sighinolfi, Laura ; Nasta, Paola ; Suter, Fredy. / The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens. In: Antiviral Therapy. 2006 ; Vol. 11, No. 7. pp. 923-929.

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AU - Torti, Carlo

AU - Arici, Claudio

AU - Antinori, Andrea

AU - Quiros-Roldan, Eugenia

AU - Minoli, Lorenzo

AU - Sighinolfi, Laura

AU - Nasta, Paola

AU - Suter, Fredy

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The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

Abstract

ASJC Scopus subject areas

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