The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

Franco Maggiolo, Diego Ripamonti, Carlo Torti, Claudio Arici, Andrea Antinori, Eugenia Quiros-Roldan, Lorenzo Minoli, Laura Sighinolfi, Paola Nasta, Fredy Suter

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: One of the more vigorous debates in the field of highly active antiretroviral therapy (HAART) is how to start it and what the optimal drug sequence is. Methods: A retrospective cohort analysis was performed. The aim was to evaluate which variables could influence the virological response to second-line genotypic-based HAART in patients with virological documented first-line HAART failure. A positive response was defined as a confirmed HIV RNA level

Original languageEnglish
Pages (from-to)923-929
Number of pages7
JournalAntiviral Therapy
Volume11
Issue number7
Publication statusPublished - 2006

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Highly Active Antiretroviral Therapy
HIV-1
Mutation
Pharmaceutical Preparations
Cohort Studies
HIV
RNA

ASJC Scopus subject areas

  • Pharmacology

Cite this

The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens. / Maggiolo, Franco; Ripamonti, Diego; Torti, Carlo; Arici, Claudio; Antinori, Andrea; Quiros-Roldan, Eugenia; Minoli, Lorenzo; Sighinolfi, Laura; Nasta, Paola; Suter, Fredy.

In: Antiviral Therapy, Vol. 11, No. 7, 2006, p. 923-929.

Research output: Contribution to journalArticle

Maggiolo, F, Ripamonti, D, Torti, C, Arici, C, Antinori, A, Quiros-Roldan, E, Minoli, L, Sighinolfi, L, Nasta, P & Suter, F 2006, 'The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens', Antiviral Therapy, vol. 11, no. 7, pp. 923-929.
Maggiolo, Franco ; Ripamonti, Diego ; Torti, Carlo ; Arici, Claudio ; Antinori, Andrea ; Quiros-Roldan, Eugenia ; Minoli, Lorenzo ; Sighinolfi, Laura ; Nasta, Paola ; Suter, Fredy. / The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens. In: Antiviral Therapy. 2006 ; Vol. 11, No. 7. pp. 923-929.
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