The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

Franco Maggiolo; Diego Ripamonti; Carlo Torti; Claudio Arici; Andrea Antinori; Eugenia Quiros-Roldan; Lorenzo Minoli; Laura Sighinolfi; Paola Nasta; Fredy Suter

The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

Franco Maggiolo, Diego Ripamonti, Carlo Torti, Claudio Arici, Andrea Antinori, Eugenia Quiros-Roldan, Lorenzo Minoli, Laura Sighinolfi, Paola Nasta, Fredy Suter

Research output: Contribution to journal › Article › peer-review

Abstract

Background: One of the more vigorous debates in the field of highly active antiretroviral therapy (HAART) is how to start it and what the optimal drug sequence is. Methods: A retrospective cohort analysis was performed. The aim was to evaluate which variables could influence the virological response to second-line genotypic-based HAART in patients with virological documented first-line HAART failure. A positive response was defined as a confirmed HIV RNA level

Original language	English
Pages (from-to)	923-929
Number of pages	7
Journal	Antiviral Therapy
Volume	11
Issue number	7
Publication status	Published - 2006

ASJC Scopus subject areas

Pharmacology

Cite this

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author = "Franco Maggiolo and Diego Ripamonti and Carlo Torti and Claudio Arici and Andrea Antinori and Eugenia Quiros-Roldan and Lorenzo Minoli and Laura Sighinolfi and Paola Nasta and Fredy Suter",

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T1 - The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

AU - Maggiolo, Franco

AU - Ripamonti, Diego

AU - Torti, Carlo

AU - Arici, Claudio

AU - Antinori, Andrea

AU - Quiros-Roldan, Eugenia

AU - Minoli, Lorenzo

AU - Sighinolfi, Laura

AU - Nasta, Paola

AU - Suter, Fredy

PY - 2006

Y1 - 2006

N2 - Background: One of the more vigorous debates in the field of highly active antiretroviral therapy (HAART) is how to start it and what the optimal drug sequence is. Methods: A retrospective cohort analysis was performed. The aim was to evaluate which variables could influence the virological response to second-line genotypic-based HAART in patients with virological documented first-line HAART failure. A positive response was defined as a confirmed HIV RNA level

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The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens

Abstract

ASJC Scopus subject areas

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