The effect of hyperventilation on motor cortical inhibition in humans: a study of the electromyographic silent period evoked by transcranial brain stimulation

A. Priori, A. Berardelli, B. Mercuri, M. Inghilleri, M. Manfredi

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the effects of hyperventilation under control of the end-tidal PCO2, on the electromyographic silent period evoked by transcranial magnetic brain stimulation and by peripheral nerve stimulation. We also studied the effects of hyperventilation on the threshold, latency and amplitude of motor potentials. Hyperventilation significantly reduced the duration of the cortical silent period, but did not affect the length of the peripheral silent period. Neither did it alter the latency, amplitude or threshold of the motor potentials. These findings suggest that hyperventilation selectively depresses motor cortical inhibition in humans.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalElectroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
Volume97
Issue number1
DOIs
Publication statusPublished - 1995

Keywords

  • Cortical inhibition
  • Hyperventilation
  • PCO
  • Respiratory alkalosis
  • Silent period
  • Transcranial brain stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'The effect of hyperventilation on motor cortical inhibition in humans: a study of the electromyographic silent period evoked by transcranial brain stimulation'. Together they form a unique fingerprint.

Cite this