The effect of oxine-5-sulphonic acid on the hepatic drug metabolism in the rat

L. Manzo, R. Passoni, A. D. Segre, F. Bertè, A. Crema

Research output: Contribution to journalArticle

Abstract

Oxine-5-sulphonic acid inhibits the metabolism of aminopyrine in the rat liver in vitro. The characteristics of this inhibition vary according to whether the oxidative N-demethylation of the substrate is determined by the formation of the metabolite 4-aminoantipyrine or by the production of formaldehyde.

Original languageEnglish
Pages (from-to)1318-1320
Number of pages3
JournalExperientia
Volume32
Issue number10
DOIs
Publication statusPublished - Oct 1976

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'The effect of oxine-5-sulphonic acid on the hepatic drug metabolism in the rat'. Together they form a unique fingerprint.

Cite this