TY - JOUR
T1 - The effect of red cells on platelet aggregation
T2 - A study with the electronic whole blood aggregometer
AU - Balduini, C. L.
AU - Bertolino, G.
AU - Noris, P.
AU - Ascari, E.
PY - 1988
Y1 - 1988
N2 - Platelet aggregation was studied in the same platelet rich plasma (PRP) by the simultaneous use of Born's optical method and Cardinal's electronic method. The maximum rate of impedance change (electronic method) correlated well with both the rate and the extent of aggregation as measured by the optical method. The rate of impedance change was therefore the parameter chosen for the study of the effect of red cells on platelet aggregation. Erythrocytes, both at 40 and 60% haematocrit (Hct.), greatly inhibited platelet aggregation induced by ADP and adrenalin, but only minimally affected platelet aggregation induced by collagen.
AB - Platelet aggregation was studied in the same platelet rich plasma (PRP) by the simultaneous use of Born's optical method and Cardinal's electronic method. The maximum rate of impedance change (electronic method) correlated well with both the rate and the extent of aggregation as measured by the optical method. The rate of impedance change was therefore the parameter chosen for the study of the effect of red cells on platelet aggregation. Erythrocytes, both at 40 and 60% haematocrit (Hct.), greatly inhibited platelet aggregation induced by ADP and adrenalin, but only minimally affected platelet aggregation induced by collagen.
KW - Platelets
KW - Red cells
KW - Whole blood platelet aggregation
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U2 - 10.3109/00365518809167505
DO - 10.3109/00365518809167505
M3 - Article
C2 - 3238314
AN - SCOPUS:0023932362
VL - 48
SP - 337
EP - 340
JO - Scandinavian Journal of Clinical and Laboratory Investigation
JF - Scandinavian Journal of Clinical and Laboratory Investigation
SN - 0036-5513
IS - 4
ER -