TY - JOUR
T1 - The effect of tms on visual motion sensitivity
T2 - An increase in neural noise or a decrease in signal strength?
AU - Ruzzoli, Manuela
AU - Abrahamyan, Arman
AU - Clifford, Colin W G
AU - Marzi, Carlo A.
AU - Miniussi, Carlo
AU - Harris, Justin A.
PY - 2011/7
Y1 - 2011/7
N2 - The underlying mechanisms of action of transcranial magnetic stimulation (TMS) are still a matter of debate. TMS may impair a subject's performance by increasing neural noise, suppressing the neural signal, or both. Here, we delivered a single pulse of TMS (spTMS) to V5/MT during a motion direction discrimination task while concurrently manipulating the level of noise in the motion stimulus. Our results indicate that spTMS essentially acts by suppressing the strength of the relevant visual signal. We suggest that TMS may induce a pattern of neural activity that complements the ongoing activation elicited by the sensory signal in a manner that partially impoverishes that signal
AB - The underlying mechanisms of action of transcranial magnetic stimulation (TMS) are still a matter of debate. TMS may impair a subject's performance by increasing neural noise, suppressing the neural signal, or both. Here, we delivered a single pulse of TMS (spTMS) to V5/MT during a motion direction discrimination task while concurrently manipulating the level of noise in the motion stimulus. Our results indicate that spTMS essentially acts by suppressing the strength of the relevant visual signal. We suggest that TMS may induce a pattern of neural activity that complements the ongoing activation elicited by the sensory signal in a manner that partially impoverishes that signal
KW - V5/MT; single pulse of transcranial magnetic stimulation
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U2 - 10.1152/jn.00746.2010
DO - 10.1152/jn.00746.2010
M3 - Article
C2 - 21543749
AN - SCOPUS:79960054395
VL - 106
SP - 138
EP - 143
JO - Journal of Neurophysiology
JF - Journal of Neurophysiology
SN - 0022-3077
IS - 1
ER -