The Effectiveness of a manual therapy and exercise protocol in patients with thumb carpometacarpal osteoarthritis: A randomized controlled trial

Jorge H. Villafañe, Joshua A. Cleland, César Fernández-De-Las-Peñas

Research output: Contribution to journalArticlepeer-review

Abstract

STUDY DESIGN: Double-blind, randomized controlled trial. OBJECTIVE: To examine the effectiveness of a manual therapy and exercise approach relative to a placebo intervention in individuals with carpo metacarpal (CMC) joint osteoarthritis (OA). BACKGROUND: Recent studies have reported the outcomes of exercise, joint mobilization, and neural mobilization interventions used in isolation in patients with CMC joint OA. However, it is not known if using a combination of these interven tions as a multimodal approach to treatment would further improve outcomes in this patient population. METHODS: Sixty patients, 90% female (mean ± SD age, 82 ± 6 years), with CMC joint OA were randomly assigned to receive a multimodal manual treatment approach that included joint mobilization, neural mobilization, and exercise, or a sham intervention, for 12 sessions over 4 weeks. The primary outcome measure was pain. Second ary outcome measures included pressure pain threshold over the first CMC joint, scaphoid, and hamate, as well as pinch and strength measure ments. All outcome measures were collected at baseline, immediately following the intervention, and at 1 and 2 months following the end of the in tervention. Mixed-model analyses of variance were used to examine the effects of the interventions on each outcome, with group as the between-subject variable and time as the within-subject variable. RESULTS: The mixed-model analysis of vari ance revealed a group-by-time interaction (F = 47.58, P

Original languageEnglish
Pages (from-to)204-213
Number of pages10
JournalJournal of Orthopaedic and Sports Physical Therapy
Volume43
Issue number4
DOIs
Publication statusPublished - Apr 2013

Keywords

  • Arthritis
  • CMC
  • Joint mobilization
  • Neural mobilization

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation

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