The effectiveness of photodynamic therapy on planktonic cells and biofilms and its role in wound healing

Steven L. Percival; Louise Suleman; Iolanda Francolini; Gianfranco Donelli

doi:10.2217/fmb.14.59

The effectiveness of photodynamic therapy on planktonic cells and biofilms and its role in wound healing

Steven L. Percival, Louise Suleman, Iolanda Francolini, Gianfranco Donelli

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

Photodynamic therapy (PDT) is the application of a photoactive dye followed by irradiation that leads to the death of microbial cells in the presence of oxygen. Its use for controlling biofilms has been documented in many areas, particularly oral care. However, the potential use of PDT in the treatment of chronic wound-associated microbial biofilms has sparked much interest in the field of wound care. The aim of this article is to provide an overview on the effectiveness of PDT on in vitro and in vivo biofilms, their potential application in both the prevention and management of wound biofilm infections and their prospective role in the enhancement of wound healing.

Original language	English
Pages (from-to)	1083-1094
Number of pages	12
Journal	Future Microbiology
Volume	9
Issue number	9
DOIs	https://doi.org/10.2217/fmb.14.59
Publication status	Published - Sep 1 2014

Keywords

biofilms
chronic wounds
PDT
photodynamic therapy

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Medicine(all)

Access to Document

10.2217/fmb.14.59

Cite this

@article{040fba37c4d54654a45b3019cbc25816,

title = "The effectiveness of photodynamic therapy on planktonic cells and biofilms and its role in wound healing",

abstract = "Photodynamic therapy (PDT) is the application of a photoactive dye followed by irradiation that leads to the death of microbial cells in the presence of oxygen. Its use for controlling biofilms has been documented in many areas, particularly oral care. However, the potential use of PDT in the treatment of chronic wound-associated microbial biofilms has sparked much interest in the field of wound care. The aim of this article is to provide an overview on the effectiveness of PDT on in vitro and in vivo biofilms, their potential application in both the prevention and management of wound biofilm infections and their prospective role in the enhancement of wound healing.",

keywords = "biofilms, chronic wounds, PDT, photodynamic therapy",

author = "Percival, {Steven L.} and Louise Suleman and Iolanda Francolini and Gianfranco Donelli",

year = "2014",

month = sep,

day = "1",

doi = "10.2217/fmb.14.59",

language = "English",

volume = "9",

pages = "1083--1094",

journal = "Future Microbiology",

issn = "1746-0913",

publisher = "Future Medicine Ltd.",

number = "9",

}

TY - JOUR

T1 - The effectiveness of photodynamic therapy on planktonic cells and biofilms and its role in wound healing

AU - Percival, Steven L.

AU - Suleman, Louise

AU - Francolini, Iolanda

AU - Donelli, Gianfranco

PY - 2014/9/1

Y1 - 2014/9/1

N2 - Photodynamic therapy (PDT) is the application of a photoactive dye followed by irradiation that leads to the death of microbial cells in the presence of oxygen. Its use for controlling biofilms has been documented in many areas, particularly oral care. However, the potential use of PDT in the treatment of chronic wound-associated microbial biofilms has sparked much interest in the field of wound care. The aim of this article is to provide an overview on the effectiveness of PDT on in vitro and in vivo biofilms, their potential application in both the prevention and management of wound biofilm infections and their prospective role in the enhancement of wound healing.

AB - Photodynamic therapy (PDT) is the application of a photoactive dye followed by irradiation that leads to the death of microbial cells in the presence of oxygen. Its use for controlling biofilms has been documented in many areas, particularly oral care. However, the potential use of PDT in the treatment of chronic wound-associated microbial biofilms has sparked much interest in the field of wound care. The aim of this article is to provide an overview on the effectiveness of PDT on in vitro and in vivo biofilms, their potential application in both the prevention and management of wound biofilm infections and their prospective role in the enhancement of wound healing.

KW - biofilms

KW - chronic wounds

KW - PDT

KW - photodynamic therapy

UR - http://www.scopus.com/inward/record.url?scp=84908118585&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908118585&partnerID=8YFLogxK

U2 - 10.2217/fmb.14.59

DO - 10.2217/fmb.14.59

M3 - Article

C2 - 25340837

AN - SCOPUS:84908118585

VL - 9

SP - 1083

EP - 1094

JO - Future Microbiology

JF - Future Microbiology

SN - 1746-0913

IS - 9

ER -

The effectiveness of photodynamic therapy on planktonic cells and biofilms and its role in wound healing

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this