The effects of acetylcholine on bulbar respiratory related neurones - Consequences of anaesthesia by pentobarbital

M. P. Morin-Surun; J. Champagnat; M. Denavit-Saubie; S. Moyanova

doi:10.1007/BF00495944

The effects of acetylcholine on bulbar respiratory related neurones - Consequences of anaesthesia by pentobarbital

M. P. Morin-Surun, J. Champagnat, M. Denavit-Saubie, S. Moyanova

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Abstract

The effects of cholinergic agonists and antagonists applied by microiontophoresis to bulbar respiratory neurones were determined in different preparations: cats anaesthetized by pentobarbital and immobilized by gallamine triethiodide, intercollicular decerebrate cats either not immobilized or immobilized by gallamine triethiodide. Respiratory neurones located at the bulbar level exhibited a muscarinic cholinergic sensitivity in all preparations. Muscarinic responses were either excitatory or inhibitory. The number of neurones showing excitatory responses was lower under pentobarbital anaesthesia than in decerebrate cats.

Original language	English
Pages (from-to)	205-208
Number of pages	4
Journal	Naunyn-Schmiedeberg's Archives of Pharmacology
Volume	325
Issue number	3
DOIs	https://doi.org/10.1007/BF00495944
Publication status	Published - Mar 1984

Keywords

Anticholinergic agents
Cholinergic agents
Pentobarbital
Respiratory neurones

ASJC Scopus subject areas

Pharmacology

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10.1007/BF00495944

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abstract = "The effects of cholinergic agonists and antagonists applied by microiontophoresis to bulbar respiratory neurones were determined in different preparations: cats anaesthetized by pentobarbital and immobilized by gallamine triethiodide, intercollicular decerebrate cats either not immobilized or immobilized by gallamine triethiodide. Respiratory neurones located at the bulbar level exhibited a muscarinic cholinergic sensitivity in all preparations. Muscarinic responses were either excitatory or inhibitory. The number of neurones showing excitatory responses was lower under pentobarbital anaesthesia than in decerebrate cats.",

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AU - Denavit-Saubie, M.

AU - Moyanova, S.

PY - 1984/3

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KW - Anticholinergic agents

KW - Cholinergic agents

KW - Pentobarbital

KW - Respiratory neurones

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The effects of acetylcholine on bulbar respiratory related neurones - Consequences of anaesthesia by pentobarbital

Abstract

Keywords

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