Abstract
Background: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. Aims: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. Study design: Prospective study. Subjects: 36 VLBW infants ([mean (S.D.)] birthweight = 864 g (204 g); gestational age = 27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. Outcome measures: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. Results: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)] = 101.4 (9.3) vs. 92.9 (12.1), P = 0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P = 0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P = 0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P = 0.074). Conclusions: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.
| Original language | English |
|---|---|
| Pages (from-to) | 691-695 |
| Number of pages | 5 |
| Journal | Early Human Development |
| Volume | 82 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2006 |
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Keywords
- Mother-infant intervention
- Neurodevelopment outcome
- Very low birth weight infants
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
The effects of an early developmental mother-child intervention program on neurodevelopment outcome in very low birth weight infants : A pilot study. / Gianní, M. L.; Picciolini, O.; Ravasi, M.; Gardon, L.; Vegni, C.; Fumagalli, M.; Mosca, F.
In: Early Human Development, Vol. 82, No. 10, 10.2006, p. 691-695.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effects of an early developmental mother-child intervention program on neurodevelopment outcome in very low birth weight infants
T2 - A pilot study
AU - Gianní, M. L.
AU - Picciolini, O.
AU - Ravasi, M.
AU - Gardon, L.
AU - Vegni, C.
AU - Fumagalli, M.
AU - Mosca, F.
PY - 2006/10
Y1 - 2006/10
N2 - Background: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. Aims: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. Study design: Prospective study. Subjects: 36 VLBW infants ([mean (S.D.)] birthweight = 864 g (204 g); gestational age = 27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. Outcome measures: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. Results: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)] = 101.4 (9.3) vs. 92.9 (12.1), P = 0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P = 0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P = 0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P = 0.074). Conclusions: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.
AB - Background: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. Aims: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. Study design: Prospective study. Subjects: 36 VLBW infants ([mean (S.D.)] birthweight = 864 g (204 g); gestational age = 27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. Outcome measures: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. Results: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)] = 101.4 (9.3) vs. 92.9 (12.1), P = 0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P = 0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P = 0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P = 0.074). Conclusions: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.
KW - Mother-infant intervention
KW - Neurodevelopment outcome
KW - Very low birth weight infants
UR - http://www.scopus.com/inward/record.url?scp=33749042978&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749042978&partnerID=8YFLogxK
U2 - 10.1016/j.earlhumdev.2006.01.011
DO - 10.1016/j.earlhumdev.2006.01.011
M3 - Article
C2 - 16530990
AN - SCOPUS:33749042978
VL - 82
SP - 691
EP - 695
JO - Early Human Development
JF - Early Human Development
SN - 0378-3782
IS - 10
ER -