The effects of an early developmental mother-child intervention program on neurodevelopment outcome in very low birth weight infants

A pilot study

M. L. Gianní, O. Picciolini, M. Ravasi, L. Gardon, C. Vegni, M. Fumagalli, F. Mosca

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Background: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. Aims: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. Study design: Prospective study. Subjects: 36 VLBW infants ([mean (S.D.)] birthweight = 864 g (204 g); gestational age = 27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. Outcome measures: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. Results: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)] = 101.4 (9.3) vs. 92.9 (12.1), P = 0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P = 0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P = 0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P = 0.074). Conclusions: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.

Original languageEnglish
Pages (from-to)691-695
Number of pages5
JournalEarly Human Development
Volume82
Issue number10
DOIs
Publication statusPublished - Oct 2006

Fingerprint

Very Low Birth Weight Infant
Mothers
Control Groups
Gestational Age
Hand
Outcome Assessment (Health Care)
Prospective Studies

Keywords

  • Mother-infant intervention
  • Neurodevelopment outcome
  • Very low birth weight infants

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

@article{2c9d4fa46a3e4e54ad9255a9ac4b7a02,
title = "The effects of an early developmental mother-child intervention program on neurodevelopment outcome in very low birth weight infants: A pilot study",
abstract = "Background: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. Aims: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. Study design: Prospective study. Subjects: 36 VLBW infants ([mean (S.D.)] birthweight = 864 g (204 g); gestational age = 27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. Outcome measures: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. Results: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)] = 101.4 (9.3) vs. 92.9 (12.1), P = 0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P = 0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P = 0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P = 0.074). Conclusions: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.",
keywords = "Mother-infant intervention, Neurodevelopment outcome, Very low birth weight infants",
author = "Giann{\'i}, {M. L.} and O. Picciolini and M. Ravasi and L. Gardon and C. Vegni and M. Fumagalli and F. Mosca",
year = "2006",
month = "10",
doi = "10.1016/j.earlhumdev.2006.01.011",
language = "English",
volume = "82",
pages = "691--695",
journal = "Early Human Development",
issn = "0378-3782",
publisher = "Elsevier Ireland Ltd",
number = "10",

}

TY - JOUR

T1 - The effects of an early developmental mother-child intervention program on neurodevelopment outcome in very low birth weight infants

T2 - A pilot study

AU - Gianní, M. L.

AU - Picciolini, O.

AU - Ravasi, M.

AU - Gardon, L.

AU - Vegni, C.

AU - Fumagalli, M.

AU - Mosca, F.

PY - 2006/10

Y1 - 2006/10

N2 - Background: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. Aims: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. Study design: Prospective study. Subjects: 36 VLBW infants ([mean (S.D.)] birthweight = 864 g (204 g); gestational age = 27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. Outcome measures: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. Results: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)] = 101.4 (9.3) vs. 92.9 (12.1), P = 0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P = 0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P = 0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P = 0.074). Conclusions: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.

AB - Background: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. Aims: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. Study design: Prospective study. Subjects: 36 VLBW infants ([mean (S.D.)] birthweight = 864 g (204 g); gestational age = 27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. Outcome measures: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. Results: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)] = 101.4 (9.3) vs. 92.9 (12.1), P = 0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P = 0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P = 0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P = 0.074). Conclusions: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.

KW - Mother-infant intervention

KW - Neurodevelopment outcome

KW - Very low birth weight infants

UR - http://www.scopus.com/inward/record.url?scp=33749042978&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33749042978&partnerID=8YFLogxK

U2 - 10.1016/j.earlhumdev.2006.01.011

DO - 10.1016/j.earlhumdev.2006.01.011

M3 - Article

VL - 82

SP - 691

EP - 695

JO - Early Human Development

JF - Early Human Development

SN - 0378-3782

IS - 10

ER -